Association between uterine leiomyomas and the biochemical screening test results in the first and second trimester of pregnancy: a pilot study.

Objectives: The presence of the uterine leiomyomas may change the concentrations of the screening serum markers and so after the risk calculation of the fetal chromosomal abnormalities.

Purpose: To estimate the influence of the uterine leiomyomas on the first and second trimester serum markers concentrations.

Material And Methods: The studied group consisted of 127 women between 11 and 20 weeks of normal singleton pregnancy.

[Connection between uterine myomas and biochemical screening results in the first and second trimester of pregnancy].

Objectives: Uterine myomas may change the concentrations of the screening serum markers and therefore alter the risk calculation of the fetal chromosomal abnormalities. An increased risk leads to invasive diagnostics procedures which in these cases can often be technically difficult due to the presence of myomas.

Aim: The aim of this study was to assess the influence of uterine myomas on the first and second trimester serum markers concentrations and, possibly on the test results.