Publications by authors named "Dorota Gajda"

Article Synopsis
  • Donor cell engraftment is necessary for successful stem cell transplantation, but the cellular interactions in bone marrow during this process have not been well understood.
  • Researchers used mass cytometry and CITEseq to analyze bone marrow cells three months after transplantation in patients with leukemia, finding significant changes in myeloid and B-cell progenitors, indicating a shift towards inflammation-driven hematopoiesis.
  • The study concluded that bone marrow engraftment is marked by emergency hematopoiesis and an inflammatory response, particularly in patients who experienced graft-versus-host disease (GVHD).
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It has become increasingly important to monitor environment contamination by such chemicals as chemical warfare agents (CWAs) and industrial toxic chemicals (TICs), as well as radiation hazards around and inside collective protection facilities. This is especially important given the increased risk of terrorist or military attacks. The Military Institute of Chemistry and Radiometry (MICR) has constructed and developed the ALERT device for the effective monitoring of these threats.

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Introduction: MOSCATO-01 is a molecular triage trial based on on-purpose tumour biopsies to perform molecular portraits. We aimed at identifying factors associated with high tumour cellularity.

Material And Methods: Tumour cellularity (percentage of tumour cells in samples defined at pathology) was evaluated according to patient characteristics, target lesion characteristics, operators' experience and biopsy approach.

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The recovery of uranium and other valuable metals from Polish Peribaltic sandstones were examined. The solid-liquid extraction is the first stage of the technology of uranium production and it is crucial for the next stages of processing. In the laboratory experiments uranium was leached with efficiencies 71-100 % by acidic lixiviants.

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Background: Cabazitaxel, abiraterone acetate (AA), and enzalutamide have been approved for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) following docetaxel chemotherapy. Whether taxanes and next-generation androgen receptor (AR) axis inhibitors are cross-resistant or not is a subject of debate.

Objective: To evaluate the antitumour activity of cabazitaxel in mCRPC pretreated with abiraterone or enzalutamide.

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Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors have limited use as first-line treatment for mutated EGFR metastatic non-small cell lung cancer. The French National Cancer Institute has installed molecular genetics platforms implementing EGFR and KRAS testing. However, there is considerable uncertainty as to which detection methods should be applied for routine diagnosis.

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