Some markers of neuronal damage in cerebrospinal fluid of multiple sclerosis patients in relapse.

In this paper the performance of cerebrospinal fluid (CSF) protein biomarkers important for monitoring damage of brain astrocytes and neurons for MS is reviewed. We estimated neurofilament, tau and phospho-tau proteins, β-APP, Aβ, S-100B and neuron-specific enolase in CSF of MS patients during relapse. We noted elevation of neurofilament, tau and phospho-tau proteins, S-100B, neuron-specific enolase and c-terminal epitopes of β-APP; concomitantly decrease of Aβ was observed.

Level of health education among neurological patients.

The task of health education is to develop health-promoting attitudes. The training of neurological patients and their families on how to care for own health and cope with the disease is a primary task of a nurse. The aim of the study, carried out among neurological patients, was to evaluate the effectiveness of health education.