Comparison of antibacterial activity and fluoride release in tooth-colored restorative materials: Resin-modified glass ionomer, zirconomer, giomer, and cention N.

Background: Considering the important role of fluoride in preventing caries by reducing the number and activity of cariogenic bacteria and introducing new fluoride-releasing tooth-colored restorative materials, this study was performed to compare and evaluate fluoride ion release and antibacterial activity of resin-modified GI, zirconomer, giomer (Beautifil), and Cention N.

Materials And Methods: In this experimental study, eighty samples (20 samples in each group) were prepared, 10 samples for fluoride testing and 10 samples for antibacterial activity. To evaluate the release of fluoride (PPM), fluoride ion-selective electrode was used on days 1, 3, 7, 14, and 21; and antibacterial activities against were examined using direct contact test by absorption of light hourly once every 5 h and days 1, 2, and 7 using an ELISA reader with a microplate reader of 800 TS at a wavelength of 630 nm.

Microleakage of five separated nickel-titanium rotary file systems in the apical portion of the root canal.

Background: The aim of this study was to evaluate the rate of apical microleakage following the fracture of five types of nickel-titanium rotary file systems (ProTaper Universal, Mtwo, RaCe, Revo-s, HeroShaper) in the apical one-third of the canal.

Materials And Methods: In this laboratory experiment, 49 mandibular premolars were collected and randomly divided into seven groups. Root canal treatment was performed by five different rotary file systems with different cross-sections.

A novel drug delivery system using acyclovir nanofiber patch for topical treatment of recurrent herpes labialis: A randomized clinical trial.

Objectives: Topical treatment with acyclovir cream has shown low efficacy in recent studies. Nano drug delivery systems, have received much attention in recent decades. The aim of this study was to compare the efficacy of acyclovir nanofiber patch with acyclovir cream.

The -592C>A variation of IL-10 gene and susceptibility to chronic periodontitis: A genetic association study and in-silico analysis.

Objectives: Chronic periodontitis (CP) is a common inflammatory disorder with a considerable impact of genetic variations in the interleukin family on predisposition to this disease. This study aimed to investigate the association between the -592C>A polymorphism of the interleukin 10 (IL-10) gene with CP risk in an Iranian population. This experimental study was followed by a meta-analysis and in silico examination.