Publications by authors named "Dorn Dennis"
J Transl Med
September 2021
Article Synopsis
- The study investigates the role of microRNA-193-3p (miR-193-3p) in protecting the heart from injury during sepsis in mice, particularly focusing on its interaction with STAT3, a protein involved in inflammation and cell signaling.
- Researchers induced sepsis in mice and manipulated miR-193-3p levels to observe changes in cardiac function, myocardial injury, and inflammatory responses.
- Results showed that increasing miR-193-3p or decreasing STAT3 improved heart function and reduced damage caused by sepsis, suggesting miR-193-3p could be a promising target for sepsis treatment.
