Peri-Intubation Cardiac Arrest in a Patient With Hypertensive Cardiac Tamponade.

Cardiac tamponade is widely known to be associated with life-threatening hypotension and rarely with hypertension. We present the case of a 53-year-old woman with hypertension and echocardiographic features of tamponade who had a cardiac arrest on intubation. The paradoxical hypertension is thought to be due to tachycardia and increased peripheral vascular resistance resulting from the compensatory sympathetic surge following impaired cardiac filling caused by the effusion.

Sports Medicine Physician Confidence in Concussion Assessments for Postconcussion Return-to-Play Decisions.

Objective: To identify sport-related concussion (SRC) assessments sports medicine physicians perform and in which they place confidence when making return-to-play (RTP) decisions.

Design: Cross-sectional study.

Setting: Online survey.

Outcomes of free flap reconstruction for mandibular ORN: Systematic review and meta-analysis.

Objective: This study aims to evaluate the success rates and complications associated with different free flap donor sites used in surgical reconstruction for mandibular osteoradionecrosis, providing insights to aid clinical decision-making.

Data Sources: MEDLINE, Embase, Cochrane, and Web of Science.

Review Methods: Comprehensive database searches were conducted up to October 2023.

Implementation of a Preanesthetic Telehealth Visit to Reduce Day-of-Surgery Cancellations.

Purpose: The purpose of the telehealth preanesthesia clinic (PAC) is to reduce the number of day-of-surgery (DOS) cancellations through the implementation of an algorithm-based standardized protocol.

Design: A prospective quality improvement project with pre and post assessment.

Methods: One hundred and fifty preoperative and postoperative surgical chart reviews using the Focus, Analyze, Develop, Execute, and Evaluate model.

National genomic profiling of antimalarial resistance in Zambian children participating in the 2018 Malaria Indicator Survey.

The emergence of antimalarial drug resistance is a major threat to malaria control and elimination. Using whole genome sequencing of 282 samples collected during the 2018 Zambia National Malaria Indicator Survey, we determined the prevalence and spatial distribution of known and candidate antimalarial drug resistance mutations. High levels of genotypic resistance were found across Zambia to pyrimethamine, with over 94% (n=266) of samples having the triple mutant (N51, C59, and S108), and sulfadoxine, with over 84% (n=238) having the double mutant (A437 and K540).

Improved Selectivity and Stability in Methane Dry Reforming by Atomic Layer Deposition on Ni-CeO-ZrO/AlO Catalysts.

Ni can be used as a catalyst for dry reforming of methane (DRM), replacing more expensive and less abundant noble metal catalysts (Pt, Pd, and Rh) with little sacrifice in activity. Ni catalysts deactivate quickly under realistic DRM conditions. Rare earth oxides such as CeO, or as CeO-ZrO-AlO (CZA), are supports that improve both the activity and stability of Ni DRM systems due to their redox activity.

A metagenomic analysis of the phase 2 Anopheles gambiae 1000 genomes dataset reveals a wide diversity of cobionts associated with field collected mosquitoes.

The Anopheles gambiae 1000 Genomes (Ag1000G) Consortium previously utilized deep sequencing methods to catalogue genetic diversity across African An. gambiae populations. We analyzed the complete datasets of 1142 individually sequenced mosquitoes through Microsoft Premonition's Bayesian mixture model based (BMM) metagenomics pipeline.

Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in Zambia.

Background: Genomic surveillance is crucial for monitoring malaria transmission and understanding parasite adaptation to interventions. Zambia lacks prior nationwide efforts in malaria genomic surveillance among African countries.

Methods: We conducted genomic surveillance of Plasmodium falciparum parasites from the 2018 Malaria Indicator Survey in Zambia, a nationally representative household survey of children under five years of age.

Impact of Structural Changes on Energy Transfer in the Anion-Engineered Re:YO Through Low-Temperature Synthesis Approach.

Anion engineering has proven to be an effective strategy to tailor the physical and chemical properties of metal oxides by modifying their existing crystal structures. In this work, a low-temperature synthesis for rare earth (RE)-doped YOSO and YOS was developed via annealing of Y(OH) intermediates in the presence of elemental sulfur in a sealed tube, followed by a controlled reduction step. The crystal structure patterns (X-ray diffraction) and optical spectra (UV-IR) of YOSO, YOS, and crystalline YO were collected throughout the treatment steps to correlate the structural transformations (via thermogravimetric analysis) with the optical properties.

Genomics reveals heterogeneous transmission and population differentiation in Zambia and bordering countries.

Genomic surveillance plays a critical role in monitoring malaria transmission and understanding how the parasite adapts in response to interventions. We conducted genomic surveillance of malaria by sequencing 241 genomes from regions with varying levels of malaria transmission across Zambia. We found genomic evidence of high levels of within-host polygenomic infections, regardless of epidemiological characteristics, underscoring the extensive and ongoing endemic malaria transmission in the country.

The impact of delayed nonurgent surgery during the COVID-19 pandemic on surgeons in Alberta: a qualitative interview study.

Background: During the COVID-19 pandemic, nonurgent surgeries were delayed to preserve capacity for patients admitted with COVID-19; surgeons were challenged personally and professionally during this time. We aimed to describe the impact of delays to nonurgent surgeries during the COVID-19 pandemic from the surgeons' perspective in Alberta.

Methods: We conducted an interpretive description qualitative study in Alberta from January to March 2022.

Zeolite Supported Pt for Depolymerization of Polyethylene by Induction Heating.

We demonstrate that for polyethylene depolymerization with induction heating (IH), using a bifunctional (Pt- or Pt-Sn-containing zeolite) hydrocracking catalyst, we can obtain high hydrocarbon product yields (up to 95 wt % in 2 h) at a relatively low surface temperature (375 °C) and with a tunable product distribution ranging from light gas products to gasoline- to diesel-range hydrocarbons. Four zeolite types [MFI, LTL, CHA(SSZ-13), and TON] were chosen as the supports due to their varying pore sizes and structures. These depolymerization results are obtained at atmospheric pressure and without the use of H and result in an alkane/alkene mixture with virtually no methane, aromatics, or coke formation.

Solving inherited white matter disorder etiologies in the neurology clinic: Challenges and lessons learned using next-generation sequencing.

Introduction: Rare neurodevelopmental disorders, including inherited white matter disorders or leukodystrophies, often present a diagnostic challenge on a genetic level given the large number of causal genes associated with a range of disease subtypes. This study aims to demonstrate the challenges and lessons learned in the genetic investigations of leukodystrophies through presentation of a series of cases solved using exome or genome sequencing.

Methods: Each of the six patients had a leukodystrophy associated with hypomyelination or delayed myelination on MRI, and inconclusive clinical diagnostic genetic testing results.

Protein intake and postprandial hyperglycemia in children and adolescents with type 1 diabetes mellitus, a pilot study.

Background And Aims: To describe the change in glucose and the resulting postprandial hyperglycemia (PPH) that occurs after dietary protein intake (PI) in children with type 1 diabetes (T1D).

Methods: We conducted a self-controlled, non-randomized, prospective pilot study in children with T1D who were given whey protein isolate drinks (carbohydrate-free, fat-free) of increasing protein amounts (0, 12.5, 25, 37.

Generation of 3D Spheroids Using a Thiol-Acrylate Hydrogel Scaffold to Study Endocrine Response in ER Breast Cancer.

Culturing cancer cells in a three-dimensional (3D) environment better recapitulates conditions by mimicking cell-to-cell interactions and mass transfer limitations of metabolites, oxygen, and drugs. Recent drug studies have suggested that a high rate of preclinical and clinical failures results from mass transfer limitations associated with drug entry into solid tumors that 2D model systems cannot predict. Droplet microfluidic devices offer a promising alternative to grow 3D spheroids from a small number of cells to reduce intratumor heterogeneity, which is lacking in other approaches.

Impact of Sc-Modified Local Site Symmetries on Er Ion Upconversion Luminescence in YO Nanoparticles.

Rare earth (RE) doped yttria sesquioxide has been widely used as host materials for upconversion (UC) phosphors due to their high refractive index, wide band gap, and high melting point. Meanwhile, while fluoride matrices with low phonon cutoff energies exhibit stronger UC emissions, RE-doped oxides exhibit better thermal stability and higher thermal sensitivity when applied as optical temperature sensors. In this work, Sc is substituted in RE-doped YO lattices to generate smaller cation sites, enhancing the crystal field and modifying the allowed optical transitions.

Genomic Surveillance of SARS-CoV-2 in a University Community: Insights Into Tracking Variants, Transmission, and Spread of Gamma (P.1) Variant.

Background: Using a combination of data from routine surveillance, genomic sequencing, and phylogeographic analysis, we tracked the spread and introduction events of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants focusing on a large university community.

Methods: Here, we sequenced and analyzed 677 high-quality SARS-CoV-2 genomes from positive RNA samples collected from Purdue University students, faculty, and staff who tested positive for the virus between January 2021 and May 2021, comprising an average of 32% of weekly cases across the time frame.

Results: Our analysis of circulating SARS-CoV-2 variants over time revealed periods when variants of concern (VOC) Alpha (B.

Family experiences with palliative care in freestanding paediatric hospices: a scoping review.

Background: Paediatric palliative care provides supportive care to children with life-threatening or life-limiting illnesses throughout the disease trajectory. Up to 42% of children receiving palliative care in Canada will die within a freestanding paediatric hospice or designated end-of-life care bed. Few studies have assessed families' experiences of this care within freestanding paediatric hospices.

Use of Neuromuscular Ultrasound in the Diagnosis of Disulfiram Polyneuropathy.

We present the case of a 37-year-old woman with alcohol use disorder, who developed leg cramping, bilateral foot drop, and hand weakness 3 months after starting disulfiram. This was accompanied by an 18-pound involuntary weight loss. Electrophysiologic findings showed a motor predominant axonal neuropathy.

Induction Heating of Magnetically Susceptible Nanoparticles for Enhanced Hydrogenation of Oleic Acid.

Radio frequency (RF) induction heating was compared to conventional thermal heating for the hydrogenation of oleic acid to stearic acid. The RF reaction demonstrated decreased coke accumulation and increased product selectivity at comparable temperatures over mesoporous FeO catalysts composed of 28-32 nm diameter nanoparticles. The FeO supports were decorated with Pd and Pt active sites and served as the local heat generators when subjected to an alternating magnetic field.

Subconcussive changes in youth football players: objective evidence using brain vital signs and instrumented accelerometers.

Brain vital signs, measured by EEG, were used for portable, objective, neurophysiological evaluation of cognitive function in youth tackle football players. Specifically, we investigated whether previously reported pre- and post-season subconcussive changes detected in youth ice hockey players were comparably detected in football. The two objectives were to: (i) replicate previously published results showing subconcussive cognitive deficits; and (ii) the relationship between brain vital sign changes and head-impact exposure.

A Novel Mobile Device-Based Navigation System for Placement of Posterior Spinal Fixation.

Background: Spinal navigation technology has revolutionized the field of spine surgery. However, adoption has not been universal. Reasons include cost, interruption in surgical workflow, increased OR time, and potential implant incompatibility, among others.

Catalytic Depolymerization of Waste Polyolefins by Induction Heating: Selective Alkane/Alkene Production.

Low- and high-density polyethylene (LDPE/HDPE) have been selectively depolymerized, without added H, to C2-C20 + alkanes/alkenes via energy-efficient radio frequency induction heating, coupled with dual-functional heterogeneous FeO and Ni- or Pt-based catalysts. FeO was used to locally generate heat when exposed to magnetic fields. Initial results indicate that zeolite-based Ni catalysts are more selective to light olefins, while Ni supported on ceria catalysts are more selective to C7-C14 alkanes/alkenes.

Simultaneous Droplet Generation with In-Series Droplet T-Junctions Induced by Gravity-Induced Flow.

Droplet microfluidics offers a wide range of applications, including high-throughput drug screening and single-cell DNA amplification. However, these platforms are often limited to single-input conditions that prevent them from analyzing multiple input parameters (e.g.