Publications by authors named "Doris H Rosero Salazar"
Article Synopsis
- The study investigates how oropharyngeal structures like the soft palate, tongue base, and epiglottis change position and coordination during normal functions like breathing and chewing.
- Using X-ray fluoroscopy with Yucatan minipigs, researchers digitized and analyzed movements to understand the dynamics of these structures.
- Findings revealed significant differences in movement magnitudes during respiration and chewing, suggesting that each structure has a unique role which may help in understanding disorders like dysphagia and sleep apnea.
Objective: Chewing, swallowing, and respiration are synchronized oropharyngeal functions. This study aimed to analyze the dynamics and coordination during natural chewing and swallowing in relation to respiratory phases.
Design: Eight oropharyngeal muscles in minipigs were recorded using electromyography, X-ray fluoroscopy, and nasopharyngeal dynamics.
Inflammatory, oxidative, and autoimmune responses cause severe damage to the nervous system inducing loss of myelin layers or demyelination. Even though demyelination is not considered a direct cause of skeletal muscle disease there is extensive damage in skeletal muscles following demyelination and impaired innervation. In vitro and in vivo evidence using exogenous antioxidants in models of demyelination is showing improvements in myelin formation alongside skeletal muscle recovery.
View Article and Find Full Text PDFIn skeletal muscles, niche factors stimulate satellite cells to activate and induce muscle regeneration after injury. In vitro, matrigel is widely used for myoblast differentiation, however, is unsuitable for clinical applications. Therefore, this study aimed to analyze attachment and differentiation of satellite cells into myotubes on fibrin coatings with selected niche components.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated the effects of fibrin constructs enhanced with laminin-nidogen on wound healing in the soft palate of rats.
- Results showed that both types of fibrin constructs led to smaller collagen areas at 56 days post-implantation compared to empty wounds, suggesting reduced fibrosis.
- Additionally, the group with laminin-nidogen exhibited better muscle regeneration, indicating this method could improve healing in cleft soft palate repairs and significant muscle injuries.
Objective: The aim of this study was to analyze the function of the palatal muscles in vivo by real-time wireless electromyography in rats. The effects of palatal wounding were also analyzed.
Methods: Microelectrodes were implanted six rats; in the masseter muscle (two-rats) for comparison, in the unwounded soft palate (two-rats) and the soft palate that received a surgical wound (two-rats).
[Molecular mechanisms in vascular osteocartilaginous metaplasia: systematic review].
Rev Fac Cien Med Univ Nac Cordoba
May 2017
Introduction: The cartilage and bone metaplasia occurring in both the heart and blood vessels, are the result of risk factors or chronic diseases that gradually adversely affect the performance of a person in society; however, clinical signs are reversible in early and intermediate stages of alterations.
Objective: To establish how the molecular mechanisms underlying the increased vascular metaplastic changes and possible aspects of treatment and prevention.
Materials And Methods: A systematic review was performed by searching for articles indexed in PubMed, Scopus and Science Direct data from 1995 to 2015.