Prevalence of Breast Cancer Subtypes Among Different Ethnicities and Bangladeshi Women: Demographic, Clinicopathological, and Integrated Cancer Informatics Analysis.

Background: The molecular subtyping of breast cancer is related to estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). The present study aimed to systematically analyze the expression, function, and prognostic value of ER, PR, HER2, and their prevalence in different ethnic groups and among Bangladeshi breast cancer (BC) patients.

Method: This study included 25 BC patients and 25 healthy controls, aged between 25 and 70 years.

EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib.

Expression of TFAP2C in luminal breast cancer is associated with reduced survival and hormone resistance, partially explained through regulation of RET. TFAP2C also regulates EGFR in HER2 breast cancer. We sought to elucidate the regulation and functional role of EGFR in luminal breast cancer.

[Laparoscopic surgery during the second trimester of pregnancy: indications, technique, and fetal repercussions. Report of nine cases and review the literature].

Non-obstetric abdominopelvic surgery during pregnancy is associated with a considerable materno-foetal complication rate related to the delayed diagnostic and therapeutic management and the severity of the underlying disease. Based on retrospective analysis of 9 laparoscopies performed during the second trimester of pregnancy between the months of January 1994 and October 1996 in the Gynaecology and Obstetrics Department of Hospital Bichat, the authors study the feasibility of this technique. They report 9 cases of abdominopelvic disease, in which laparoscopy allowed a diagnostic and therapeutic approach: 6 cases of adnexal disease, 2 appendicular syndromes and one diagnostic laparoscopy.

[Ultrasonographic signs of chromosome aberrations].

We reviewed the literature on ultrasonographic criteria allowing prenatal diagnosis of chromosome aberrations, especially the most frequent: trisomy. Signs vary depending on the term of the ultrasound examination (first trimester ultrasound is often performed to early and several signs are observed in the second trimester). During the first trimester, the main criteria is the diagnosis of nuchal clearness 3 mm.