Publications by authors named "Doreen Khan-Lim"

Purpose: To assess the effect of upper eyelid blepharoplasty surgery on contrast sensitivity.

Methods: A prospective study was performed. Pre- and postoperative contrast sensitivity measurements were taken on patients undergoing routine upper eyelid blepharoplasty surgery.

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Childhood pterygia are extremely rare and no consensus currently exists regarding surgical management in cases of significant symptomatology. The authors describe a case of a childhood pterygium in a 9-year-old boy successfully treated with a superior conjunctival autograft. At 6 months of follow-up, no signs of recurrence were detected and the patient reported marked improvement in symptoms.

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Background: Optic disk pits are known as congenital cavitary defects associated with serous detachment of the retina; 75% of such cases do not resolve spontaneously, and surgical management is required. The use of gas or oil tamponade in these cases has been associated with detachment of the retina attributed to the passage of intravitreal gas or fluid via the disk pit and into the subretinal space. Prophylactic peripapillary laser retinopexy is therefore recommended peroperatively to create a barrier to fluid flow between the vitreous cavity and the subretinal space.

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We have surveyed the ophthalmic literature of the last five years in an attempt to evaluate the use and usefulness of Rose Bengal staining as an aid to differential diagnosis in dry eyes. Included both as a criterion and as an adjunct measure of disease progression, Rose Bengal scores of patients with different dry eye conditions overlap, sometimes to a considerable extent. A mechanistic link between staining with this dye and disease etiology is unlikely; however, Rose Bengal could be a surrogate marker of changes in ocular surface physiology.

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Interactions between leucocytes and their surroundings are mediated through oligosaccharide epitopes, some of which are also expressed on ocular mucins. Neutrophils represent the majority of immune cells in the proinflammatory environment of the ocular surface during sleep. We have tested whether changes in mucin glycosylation, as occur in dry eyes, influence the phenotype and activation of neutrophils.

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Purpose: To determine the relative importance of patients' motives for having laser in situ keratomileusis (LASIK) for myopia.

Setting: The Corneal Diseases and Excimer Laser Research Unit, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland.

Methods: Twenty-one cards printed with potential reasons for having LASIK and 3 blank cards for respondents to include additional motives were posted to 71 patients who had myopic LASIK.

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