Publications by authors named "Doreen A Kahangire"

Article Synopsis
  • The study focused on treatment patterns and the time it took for patients with advanced non-small cell lung cancer (NSCLC) to receive results from epidermal growth factor receptor (EGFR) mutation tests, which are important for targeted therapy.
  • It analyzed data from 1,793 patients across various countries, showing that most received their test results within two weeks, but over a third had already started treatment before getting those results.
  • The findings highlighted significant delays for some patients, with 20% not receiving EGFR-targeted treatments, indicating variability in treatment approaches across different countries.
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Article Synopsis
  • The study investigates the relationship between achieved low-density lipoprotein cholesterol (LDL-C) levels and healthcare costs in patients who underwent lipid-lowering therapy after a recent myocardial infarction (heart attack) in Spain.
  • Out of 6025 patients analyzed, only 11% met the LDL-C goals set by 2016 guidelines, and a mere 1% reached the more stringent goals of the 2019 guidelines.
  • Achieving lower LDL-C levels was linked to significantly reduced healthcare resource use and costs, suggesting that more intensive lipid-lowering treatments could be economically and clinically beneficial.
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Unlabelled: The use of anti-osteoporosis treatment following a diagnosis of osteoporosis with fracture or a relevant fragility fracture remains low in France. Initiating an anti-resorptive may reduce the incidence of a subsequent fracture by 60%.

Purpose: To describe real-world osteoporosis treatment patterns in individuals with a fragility fracture in France and to explore the impact of initiating treatment on the risk of subsequent fracture.

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Introduction: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of mortality in Italy, accounting for 22% of total deaths. Lowering low-density lipoprotein cholesterol (LDL-C) levels reduces the risk of cardiovascular (CV) events; thus, lipid-lowering therapy (LLT) is the first-line treatment for patients with ASCVD and hypercholesterolaemia. However, many patients with ASCVD fail to reach LDL-C treatment thresholds, leaving them at greater risk of CV events.

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Unlabelled: Osteoporosis is a skeletal disease that may result in low-trauma fracture if untreated. Among men and women ≥ 70 years untreated for osteoporosis, 30% (43,514) sustained at least one post-index fracture. Care for patients with osteoporosis diagnosis directly contributed to a cost burden of €786 million.

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