Publications by authors named "Dora Moffatt"
Proteoglycan Res
November 2024
Article Synopsis
- Accumulation of hyaluronan (HA) in the lungs is a common response to lung injury, particularly during Nb infection, which leads to tissue damage and prompts a type 2 immune response.
- HA levels peaked seven days post-infection, correlating with lung damage and immune involvement, specifically characterized by eosinophils and increased IL-13 cytokines.
- The study shows that HA accumulation is dependent on IL-13, highlighting its role in regulating the HA matrix and supporting lung tissue repair during inflammatory responses.
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