Publications by authors named "Dora Merkl"
Importance: Neurofeedback has been proposed for the treatment of attention-deficit/hyperactivity disorder (ADHD) but the efficacy of this intervention remains unclear.
Objective: To conduct a meta-analysis of randomized clinical trials (RCTs) using probably blinded (ie, rated by individuals probably or certainly unaware of treatment allocation) or neuropsychological outcomes to test the efficacy of neurofeedback as a treatment for ADHD in terms of core symptom reduction and improved neuropsychological outcomes.
Data Sources: PubMed (MEDLINE), Ovid (PsycInfo, MEDLINE, Embase + Embase Classic), and Web of Science, as well as the reference lists of eligible records and relevant systematic reviews, were searched until July 25, 2023, with no language limits.
Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder that primarily affects the cortico-basal ganglia-thalamo-cortical (CBGTC) circuitry and is characterized by motor and vocal tics. Previous studies have found enhancement in procedural memory, which depends on the CBGTC circuitry and plays an important role in the learning and processing of numerous motor, social, and cognitive skills and habits. Based on these studies, procedural hyperfunctioning in TS has been proposed.
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- Tourette syndrome primarily manifests as motor and vocal tics, but it can also include some cognitive changes, with limited evidence of learning impairment in patients.
- The disorder is linked to dysfunctions in the basal ganglia and frontostriatal loops, impacting the acquisition phase of associative learning tasks.
- In a study using a modified learning test, Tourette syndrome patients, especially those with comorbid conditions, showed poor performance in forming associations, but retrieval and generalization abilities remained unaffected.