Publications by authors named "Dora K Farkas"
Background: Evidence of an association between trigeminal neuralgia (TN) and subsequent cancer risk remains sparse. The present study aimed to examine the association between TN and cancer risk in the Danish population.
Methods: A nationwide population-based cohort study using hospital diagnoses collected routinely and prospectively from Danish population-based registries in 1994-2022.
Article Synopsis
- The study aimed to explore whether certain genetic variants (SNPs) related to taxane chemotherapy affect breast cancer patients' need for social benefits after treatment.
- Researchers analyzed data from premenopausal women diagnosed with breast cancer, focusing on their receipt of health and labor market-related benefits over a five-year period.
- The findings indicated that there was no significant link between the selected SNPs and the likelihood of receiving social benefits post-chemotherapy.
Educational, labour market and relationship outcomes in people with acne.
J Eur Acad Dermatol Venereol
September 2024
Background: Although acne is associated with scarring, mental health comorbidities and bullying, little is known about its impact on socio-economic outcomes.
Objectives: To examine the association between acne and educational, labour market and relationship outcomes.
Methods: We conducted a nationwide registry-based cohort study in Denmark.
Background: Urticaria has been tentatively linked to cancer, but epidemiological evidence supporting this link is sparse and conflicting. We conducted a population-based cohort study using healthcare databases covering the Danish population (January 1980-December 2022). We followed 87 507 people for a median of 10.
View Article and Find Full Text PDFPURPOSESocial characteristics, including cohabitation/marital status and socioeconomic position (SEP)-education level, employment status, and income-influence breast cancer prognosis. We investigated the impact of these social characteristics on adherence to adjuvant endocrine therapy (AET) from treatment initiation to 5 years after diagnosis.METHODSWe assembled a nationwide, population-based cohort of premenopausal women diagnosed in Denmark with stage I-III, estrogen receptor-positive breast cancer during 2002-2011.
View Article and Find Full Text PDFAim: To examine the risk of second primary cancer in patients with incident renal cell carcinoma (RCC).
Methods: We identified all patients diagnosed with incident RCC during 1995-2019, using population-based Danish medical registries. Patients were followed from the date of RCC diagnosis until any second primary cancer diagnosis, death, emigration, or December 31, 2019, whichever came first.
Article Synopsis
- The study analyzed the social benefit use of women diagnosed with breast cancer in Denmark from 2002 to 2011, focusing on how education and cohabitation influenced their work abilities and need for support.
- About 81.8% of women were self-supporting before diagnosis, but ten years later, this number dropped to 69%, with notable increases in disability pensions and flexi jobs, especially among those with lower education and living alone.
- The findings highlight that less educated women and those living alone experienced greater challenges in maintaining work and higher reliance on social benefits, emphasizing the need for targeted support for these groups.
Introduction: Patients with hormone receptor positive breast cancer are recommended at least five years of adjuvant endocrine therapy, but adherence to this treatment is often suboptimal. We investigated longitudinal trends in adjuvant endocrine therapy (AET) adherence among premenopausal breast cancer patients and identified clinical characteristics, including baseline comorbidities and non-cancer chronic medication use, associated with AET adherence.
Methods: We included stage I-III premenopausal breast cancer patients diagnosed during 2002-2011 and registered in the Danish Breast Cancer Group clinical database who initiated AET.
Risk of Cancer in Patients With Diverticular Disease: A Population-Based Cohort Study.
Clin Gastroenterol Hepatol
October 2024
Background & Aims: Several studies have investigated the association between diverticular disease (DD) and colorectal cancer. However, whether there is an association between DD and malignancies other than those in the colorectum remains uncertain.
Methods: For the 1978-2019 period, we conducted a nationwide, population-based cohort study using national Danish health care data.
Importance: The burden of caring for children with complex medical problems such as major congenital anomalies falls principally on mothers, who in turn suffer a variety of potentially severe economic consequences. As well, health consequences of caregiving often further impact the social and economic prospects of mothers of children with major congenital anomalies (MCMCAs). Evaluating the long-term economic consequences of extensive in-home caregiving among MCMCAs can inform strategies to mitigate these effects.
View Article and Find Full Text PDFBackground: Despite the known mental health burden among children with congenital heart disease (CHD), the literature is constrained by a lack of comparison cohorts and population-based follow-up data. We examined the incidence of mental health conditions among children with CHD, relative to 3 comparison cohorts.
Methods: This population-based cohort study identified all children with CHD (<18 years of age; n=16 473) in Denmark from 1996 to 2017, through linkage of individual-level data across national registries.
Background: Whether cerebral venous thrombosis (CVT) is a marker of cancer in clinical practice remains unknown. Little is known about the prognosis of cancer detected subsequent to CVT.
Methods: We used Danish nationwide registries (1996-2019) to identify patients with a first-time primary inpatient diagnosis of CVT without a history of cancer (N=811, 65% women, median age 42 years).
Background: Venous thromboembolism (VTE) may be a harbinger of cancer in the general population. Patients with kidney disease have an a priori increased VTE risk. However, it remains unknown how a VTE affects subsequent cancer risk in these patients.
View Article and Find Full Text PDFBackground: Real-world data in form of routinely collected clinical data are a valuable resource for epidemiological research in infectious disease. We examined the validity of a discharge diagnosis of fever of unknown origin from hospital discharge registries.
Methods: We identified patients with a first in- or outpatient diagnosis (primary or secondary) of fever of unknown origin (ICD-10 code R50.
Background: Breast cancer survivors may have increased risk of subsequent haematologic cancer. We compared their risk of haematologic cancers with the general population during 38 years of follow-up.
Methods: Using population-based Danish medical registries, we assembled a nationwide cohort of women diagnosed with incident non-metastatic breast cancer during 1980-2017, with follow-up through 2018.
Aspirin may reduce the risk of cancer, particularly gastrointestinal cancer, and venous thromboembolism (VTE). VTE can be the first symptom of occult cancer, but whether it is also a marker of occult cancer in aspirin users remains unknown. Therefore, we investigated the risk of cancer subsequent to VTE among users of low-dose aspirin.
View Article and Find Full Text PDFIntroduction: It is unclear whether Guillain-Barré syndrome (GBS) can be a marker of a paraneoplastic syndrome. We examined whether GBS is associated with cancer and whether the prognosis of GBS patients with cancer differs from that of other cancer patients.
Materials And Methods: We conducted a population-based cohort study of patients diagnosed with GBS between 1978 and 2017 using Danish registry-data.
Purpose: We examined the effect of olodaterol on the risk of myocardial ischaemia, cardiac arrhythmia, and all-cause mortality compared with use of other long-acting beta2-agonists (LABAs). Channelling bias was also explored.
Methods: This Danish population-based cohort study used data linked from registries of hospital diagnoses, outpatient dispensings, and deaths.
Purpose: Data on long-term mortality among patients with hospital-diagnosed overweight/obesity are limited. Thus, we aim to examine 40-year mortality among patients with hospital-diagnosed overweight/obesity, including cause-specific deaths, secular time trends, and potential effect modification by age, comorbidity, and socioeconomic factors.
Patients And Methods: From national registries, we identified all Danes with a first hospital-based overweight/obesity diagnosis (N=331,185), 1979-2018, and constructed an age- and gender-matched general population comparison cohort (N=1,655,925).
Background: Strong evidence indicates that venous thromboembolism is a presenting symptom of cancer. Cancer is a known cause of pulmonary hypertension; however, it remains unknown whether pulmonary hypertension is a marker of occult cancer. We examined the association between a pulmonary hypertension diagnosis and cancer risk in a cohort study using population-based data from the Danish health system.
View Article and Find Full Text PDFBackground: Diagnostic tools for determining causes of fever of unknown origin (FUO) have improved over time. We examined if cancer incidence among these patients changed over a 20-year period.
Methods: Population-based cohort study using nationwide Danish registries.
Objective: The purpose of this study was to examine overall and site-specific cancer risk among individuals diagnosed with migraine compared with the general population.
Background: Current evidence regarding migraine and risk of cancer is sparse and inconclusive.
Methods: We conducted a nationwide population-based cohort study with data collected routinely and prospectively from Danish population-based registries from 1995 to 2017.
Objective: To examine the risk of urogenital, colorectal, and neurological cancers after a first diagnosis of acute urinary retention.
Design: Nationwide population based cohort study.
Setting: All hospitals in Denmark.