Publications by authors named "Dora Alonso Rosa"
Background And Objectives: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired clonal disease characterized by complement-mediated hemolysis, bone marrow failure and thrombosis. Eculizumab is a humanized monoclonal antibody that blocks the cytolytic component of the complement system by binding to complement C5.
Material And Methods: We report the results of eculizumab treatment in 25 PNH patients from different centers in Spain.