Skin Anti-Aging Potential through Whitening and Wrinkle Improvement Using Fermented Oil Derived from Larvae.

As the aging population increases, so has interest among emerging seniors in anti-aging ingredients that enhance functionality by incorporating fermentation with natural materials. In this study, fermentation conditions for enhancing the functionality of larvae oil (HIO) were established, and its anti-aging potential was evaluated. First, the lipase activity and amount of lipid degradation products of the fermentation strains were measured in order to select and as the strains with high fermentation ability.

Development of Optimized Feed for Lipid Gain in (Coleoptera: Tenebrionidae) Larvae.

Super mealworm (Coleoptera: Tenbrionidea) larvae (ZML) are being investigated as potential candidates for biodiesel production. Several studies have revealed that the crude fat content of ZML can be enhanced by increasing the feed consumed. We aimed to develop an optimized ZML feed that enhances the lipid gain using 10 different ingredients.

Prediction of intestinal stem cell regulatory genes from Drosophila gut damage model created using multiple inducers: Differential gene expression-based protein-protein interaction network analysis.

Intestinal tissue functions in innate immunity to prevent the entry of harmful substances, and to maintain homeostasis through the constant proliferation of intestinal stem cells (ISC). To understand the mechanisms which regulate ISC in response to gut damage, we identified 81 differentially expressed genes (DEGs) through RNA-seq analysis after oral administration of three intestinal-damaging substances to Drosophila melanogaster. Through protein-protein interaction (PPI) and functional annotation studies, the top 22 DEGs ordered by the number of nodes in the PPI network were analyzed in relation to cell development.

Potential of Antimicrobial Peptide-Overexpressed Larvae Extract as a Natural Preservative for Korean Traditional Sauces.

Here, we aimed to produce a natural food preservative using a crude extract from edible, immunized larvae (iTME), injected with edible bacteria using an edible solvent. Results showed that iTME had concentration-dependent inhibitory activity against food-poisoning bacteria , , and , as well as against harmful fungi , , and . Moreover, iTME showed antimicrobial activity against beneficial microorganisms and , but not .

Effect of Feed Containing Larvae Immunized by Injection on the Growth and Immunity of Rainbow Trout ().

We investigated the effects of a feed containing larvae injected with bacteria on the growth and immunity of . The feed was prepared by replacing fishmeal in feed with 25 and 50% nonimmunized (HIL25, HIL50) or immunized HIL (ImHIL25, ImHIL50), and its protein:fat:carbohydrate ratio was 45:15:18. ImHIL extracts showed inhibitory activity against fish pathogenic bacteria.

In Vitro Protective Effect of Paste and Sauce Extract Made with Larvae on HepG2 Cells Damaged by Ethanol.

We made paste and sauce using protein-rich larvae (PBL) and evaluated their fermentation levels. After pretreatment with the paste and sauce extracts, HepG2 cells were damaged with ethanol (EtOH), and then the effects of the paste and sauce were evaluated. As a result, we confirmed that the PBL paste and sauce extracts reduced the aspartate aminotransferase (AST) and alanine aminotransaminase (ALT) content in the medium as compared to soybean () sauce and paste extracts.

Hemocyte Morphology and Cellular Immune Response in Termite (Reticulitermes speratus).

Because termites (Reticulitermes speratus) are very small, it is difficult to conduct experiments involving pathogen injection and hemocyte collection. Therefore, to observe hemocyte-mediated immune responses against foreign substances, in vitro hemocyte culture is essential. After collecting about 3 μl of hemolymph, hemocytes were cultured for 7 d, during which the cells maintained full function.