Clinical outcomes of surgical management for recurrent rectal prolapse: a multicenter retrospective study.

Purpose: There are few reports on outcomes following surgical repair of recurrent rectal prolapse. The purpose of this study was to examine surgical outcomes for recurrent rectal prolapse.

Methods: We conducted a multicenter retrospective study of patients who underwent surgery for recurrent rectal prolapse.

Laparoscopic Ventral Mesh Rectopexy (LVMR) for Internal and External Rectal Prolapse: An Analysis of 122 Consecutive Patients.

Background: Even though several reports have been published on the results of laparoscopic ventral mesh rectopexy (LVMR) in Asia, there are few mid-term or long-term results of LVMR. The authors aimed to evaluate the results of LVMR in patients with internal rectal prolapse (IRP) external rectal prolapse (ERP).

Materials And Methods: From September 2013 to January 2019, 122 patients with IRP (n=48) or ERP (n=74) underwent LVMR.

Nomogram Development and External Validation for Predicting the Risk of Lymph Node Metastasis in T1 Colorectal Cancer.

Purpose: Predicting lymph node metastasis (LNM) risk is crucial in determining further treatment strategies following endoscopic resection of T1 colorectal cancer (CRC). This study aimed to establish a new prediction model for the risk of LNM in T1 CRC patients.

Materials And Methods: The development set included 833 patients with T1 CRC who had undergone endoscopic (n=154) or surgical (n=679) resection at the National Cancer Center.

Persistent Bleeding Following a Stapled Hemorrhoidopexy.

A stapled hemorrhoidopexy (SH) is widely used for treatment of patients with grades III and IV hemorrhoids. The SH is easy to perform, is associated with less pain and allows early return to normal activities. However, complications, whether severe or not, have been reported.

Rectal neuroendocrine and L-cell tumors: diagnostic dilemma and therapeutic strategy.

Rectal neuroendocrine tumors (NETs) are currently divided into L-cell and non-L-cell types. In the World Health Organization 2010 classification, L-cell tumors are defined as borderline, whereas non-L-cell tumors are considered to represent malignancies. To establish differential diagnostic criteria and therapeutic strategy, we investigated the pathologic features of rectal NETs associated with lymph node metastasis and the clinicopathologic significance of the L-cell phenotype.

Reduced CDX2 expression predicts poor overall survival in patients with colorectal cancer.

The homeodomain transcription factor CDX2 directs development and maintenance of normal intestinal epithelium. However, the role of CDX2 in colorectal carcinogenesis is poorly understood. Hence, we investigated the CDX2 expression in patients with colorectal cancer and its relationship to tumor cell proliferation and differentiation and evaluated the role of this molecule as a biologic marker for the prediction of poor patient survival.

Comparison of the compression anastomosis ring (EndoCAR) with a circular stapled anastomosis in a porcine model.

Purpose: The aim of this study was to compare characteristics of rectal compression and stapled anastomoses at multiple time points.

Methods: A total of 50 domestic pigs underwent a rectal anastomosis with a compression device or a circular stapler. They were sacrificed at zero-time, 2 days, 1 week, 1 month, and 3 months.

Safety of the NiTi EndoCAR following chemoradiation in a porcine model.

Purpose: To assess the safety of anastomosis ring (EndoCAR) following chemoradiation.

Methods: A total of 10 pigs received radiation to a bioequivalent dose of 4500 cGy with 4 doses of 5-fluorouracil 400 mg/m(2) and leucovorin 20 mg/m(2) intravenous bolus. On day 21, each animal underwent 2 rectal anastomoses, 10 cm apart, using a 27-mm EndoCAR device and a 29-mm circular stapler.