Depiction of dentatorubrothalamic tract fibers in patients with Parkinson's disease and multiple sclerosis in deep brain stimulation.

Background: We wanted to depict fibers of the dentatorubrothalamic tract in patients with Parkinson's disease and multiple sclerosis in order to use this knowledge for clinical routine and to show its relation to the corticospinal tract for deep brain stimulation. Fibers of these white matter tracts were depicted between February 2014 and February 2015 in nine patients of all ages. There were seven men and two women.

Subtraction of subcutaneous fat to improve the prediction of visceral adiposity: exploring a new anthropometric track in overweight and obese youth.

Background: The efficiency of traditional anthropometric measurements such as body mass index (BMI) or waist circumference (Waist C) used to replace biomedical imaging for assessing visceral adipose tissue (VAT) is still highly controversial in youth.

Hypothesis And Objectives: We evaluated the most accurate model predicting VAT in overweight/obese youth, using various anthropometric measurements and their correlation with different body fat compartments, especially by testing, for the first time in youth, the hypothesis that subtracting the anthropometric measurement the most highly correlated with subcutaneous abdominal adipose tissue (SAAT) and less correlated possible with VAT from an anthropometric abdominal measurement highly correlated with visceral and total abdominal adipose tissue (TAAT), predicts VAT with higher accuracy.

Subjects And Methods: VAT and SAAT data resulted from magnetic resonance imaging (MRI) analysis performed on 181 boys and girls (7-17 y) from Diabetes & Endocrinology Care Paediatrics Clinic in Luxembourg.

Post-operative imaging in deep brain stimulation: A controversial issue.

In deep brain stimulation (DBS), post-operative imaging has been used on the one hand to assess complications, such as haemorrhage; and on the other hand, to detect misplaced contacts. The post-operative determination of the accurate location of the final electrode plays a critical role in evaluating the precise area of effective stimulation and for predicting the potential clinical outcome; however, safety remains a priority in postoperative DBS imaging. A plethora of diverse post-operative imaging methods have been applied at different centres.

Visualization of the medial forebrain bundle using diffusion tensor imaging.

Diffusion tensor imaging is a technique that enables physicians the portrayal of white matter tracts in vivo. We used this technique in order to depict the medial forebrain bundle (MFB) in 15 consecutive patients between 2012 and 2015. Men and women of all ages were included.

Cardiometabolic risk: leg fat is protective during childhood.

Background: Childhood obesity is associated with early cardiometabolic risk (CMR), increased risk of adulthood obesity, and worse health outcomes. Leg fat mass (LFM) is protective beyond total fat mass (TFM) in adults. However, the limited evidence in children remains controversial.

Diffusion tensor imaging--arcuate fasciculus and the importance for the neurosurgeon.

Objective: Tumors in eloquent areas of the brain like Broca or Wernicke might have disastrous consequences for patients. We intended to visualize the arcuate fasciculus (AF) and to demonstrate his relation with the corticospinal tract and the visual pathway using diffusion tensor imaging (DTI).

Methods: We depicted between 2012 and 2014 the AF in 71 patients.

Posterior fossa mass in immunosuppressed patient.

Background: Toxoplasmosis is the most frequent opportunistic infection of the central nervous system among individuals with the acquired immunodeficiency syndrome. Radiographic modalities include brain CT, MRI and PET scan. The differential diagnosis are usually: primary CNS lymphoma, cerebral metastasis, Progressive multifocal leukoencephalopathy, cytomegalovirus.

Holmes tremor in a patient with progressive multifocal leukoencephalopathy.

Background: Progressive multifocal leukencephalopathy (PML) is a rare, sometimes fatal viral disease in patients with primary or secondary immunosuppression.

Case Description: A 57-year-old immunocompetent female with intractable Holmes tremor and elongated unique brainstem lesion reported to our hospital. The cerebrospinal fluid (CSF) screening for John Cunningham virus was negative and the diagnosis was established by brain biopsy.

DTI of the visual pathway - white matter tracts and cerebral lesions.

DTI is a technique that identifies white matter tracts (WMT) non-invasively in healthy and non-healthy patients using diffusion measurements. Similar to visual pathways (VP), WMT are not visible with classical MRI or intra-operatively with microscope. DIT will help neurosurgeons to prevent destruction of the VP while removing lesions adjacent to this WMT.

NOAC and intracerebral bleeding--presentation of four cases and review of the literature.

AF might be a life threatening disease. Patients have been under oral antithrombotic treatment in order to avoid thrombotic events. Although this treatment proved to be effective in the last decades there was always the inconvenience of a regular blood control.

[Radioinduced brain cyst: case report].

We present a case of intraparenchymal radioinduced cyst of the brain observed in our department. It is a rare and relatively benign pathology which is usually treated conservatively or by surgery. We emphasize long-term imaging follow up in patients treated by radiosurgery, which can lead to the demonstration of multiple adverse events such as tumefactive cyst formation.

First description of posterior reversible encephalopathy syndrome as a complication of glycerolnitrate patch following open cardiac surgery.

Background: Posterior reversible encephalopathy syndrome (PRES) affects predominantly the parietal and occipital lobes. Frequent clinical features are epileptic seizure, altered mental status and visual disturbances.

Clinical Presentation: We present the first case of a patient with pericarditis and mitral valve insufficiency, who developed PRES after application of a glycerolnitrate patch day three post-operatively and whose neurological deficits improved within 2 days after withdrawal of patch therapy.

Laser-induced fluorescence spectroscopy for phenol and intermediate products in aqueous solutions degraded by pulsed corona discharges above water.

Laser-induced fluorescence (LIF) spectroscopy is introduced as an in situ diagnostic for phenol and intermediate products in an aqueous solution degraded by corona discharges. The complications that are inherent in applying LIF as a diagnostic for aqueous solutions are experimentally examined. The LIF intensities of phenol and the intermediate products are measured as a function of time.

Camptocormia associated with focal myositis in multiple-system atrophy.

Camptocormia (CC) or pronounced forward flexion of the trunk is a common symptom of Parkinson's disease. We describe 2 patients with probable, respectively possible multiple-system atrophy and CC. Magnetic resonance imaging of the erector trunci showed focal patchy hyperintensities with gadolinium enhancement and muscle biopsy was indicative of variably pronounced focal myositis.

Apparent diffusion coefficient measurements within intracranial epidermoid cysts in six patients.

The purpose was to determine whether a strong decrease in apparent diffusion coefficient (ADC) within epidermoid cysts (ECs) is actually responsible for their bright signal intensity on diffusion-weighted (DW) trace images. We studied six patients with surgically proven ECs in whom ADC calculation from T2-weighted DW-EPI-SE data were performed within the ECs and within the deep white matter and cerebrospinal fluid (CSF) as references. All ECs displayed highest signal intensity on the DW trace images.

A double-blind clinical trial of mitoxantrone versus methylprednisolone in relapsing, secondary progressive multiple sclerosis.

A double-blind clinical trial of mitoxantrone versus methylprednisolone was performed in 49 patients with relapsing, secondary multiple sclerosis. Patients were randomized to receive 13 infusions of mitoxantrone 12 mg/m2 (n = 28), or 13 infusions of 1 g of methylprednisolone (n = 21), over 32 months. Twenty-four patients completed the trial.

[Glioma in a patient with multiple sclerosis].

The simultaneous occurrence of multiple sclerosis and a primary brain neoplasm is exceptional: only 32 cases have been reported in the literature. We report the case of a 30-year-old woman with multiple sclerosis proven for 10 years who developed a grade II astrocytoma revealed by MRI. At the pathology examination, there was no cellular continuity with areas of demyelinized white matter.

Ectopic prolactinoma in the clivus.

Background: Ectopic pituitary adenomas are rare. Only 29 cases are reported in the literature. The clivus was involved in some cases but sella turcica was occasionally involved.

[Late form with psychiatric presentation of Wilson's disease, with pseudo-compulsive stereotyped movements. Neuro-radiological correlations].

Wilson's disease rarely starts after the third decade and may present with misleading psychiatric signs. We observed a 39-year-old white male who developed hysterical behaviour followed by frank delusional psychosis. Secondary neurological symptoms like astasia and dyarthria were misinterpreted as drug-induced.

Cerebral magnetic resonance imaging in a 2-year-old Caucasian girl, with hypomelanosis of Ito.

Hypomelanosis of Ito is a rare sporadic neurocutaneous disorder. CNS abnormalities are observed in more than 50% of the cases. A case of hypomelanosis in a 2 year old girl is reported.

Radiation-induced myelopathy and vertebral necrosis.

Radiation-induced myelopathy is often a diagnosis of exclusion. In addition to the classic criteria needed to support the diagnosis, the presence of another radiation-induced lesion, such as aseptic vertebral necrosis, is useful to confirm the cause of the spinal cord lesion.

Lhermitte-Duclos disease. A case report.

We report one case of histologically proved Lhermitte-Duclos disease. Suspected on the basis of CT and angiography, the pre-operative diagnosis has been confirmed by the characteristic features of the lesion on MRI: a unilateral posterior fossa mass, hyperintense on proton density and T2-weighted images, hypointense on T1-weighted images, non enhancing after Gd administration. The gyral pattern was preserved, but a specific thickening of cerebellar folia was demonstrated.

Intravertebral vacuum cleft: changes in content after supine positioning.

Sequential radiographic and magnetic resonance (MR) imaging examinations were performed in nine patients with an intravertebral vacuum cleft indicative of avascular necrosis. Progressive changes in the content of the cleft occurred within an hour after the patients were placed in a supine position. Initially, the cleft showed a gaslike pattern during extension of the spine, with a radiolucent band on radiographs and a signal void on MR images.