Publications by authors named "Donya Bagheri"
The design, preparation and characterization of a novel composite based on functionalization of halloysite nanoclay with Schiff base followed by immobilization of copper iodide as nanoparticles is revealed. This novel nano composite was fully characterized by utilization of FTIR, SEM/EDX, TGA, XRD and BET techniques. This Cu(I) NPs immobilized onto halloysite was successfully examined as a heterogeneous, thus easily recoverable and reusable catalyst in one of classist organic name reaction so-called "Click Reaction".
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- The Adenoma Prevention with Celecoxib Trial studied celecoxib, a Cox-2 inhibitor, for preventing colorectal adenomas in high-risk patients, comparing it to a placebo.
- Results indicated that celecoxib significantly reduced adenoma incidence but raised the risk of cardiovascular events compared to placebo.
- An extension of the study found similar rates of adverse events across groups, but higher risks of cardiovascular issues for those taking celecoxib, particularly for patients with a history of heart disease.
Background: Studies showing that drugs that inhibit cyclooxygenase-2 (COX-2) reduce the number of colorectal adenomas in animals and patients with familial adenomatous polyposis suggest that COX-2 inhibitors may also prevent sporadic colorectal neoplasia.
Methods: We randomly assigned patients who had adenomas removed before study entry to receive placebo (679 patients) or 200 mg (685 patients) or 400 mg (671 patients) of celecoxib twice daily. Randomization was stratified for the use of low-dose aspirin.