Publications by authors named "Dony Yugo"
Article Synopsis
- A study investigated why some patients with paroxysmal atrial fibrillation (PAF) progress to persistent atrial fibrillation (PersAF) despite catheter ablation, focusing on predictors of this progression.
- The study included 400 PAF patients, categorizing them into three outcome groups, and monitored them for 3 years post-ablation to assess AF recurrence and progression.
- Key findings showed that a larger left atrial diameter, presence of non-pulmonary vein triggers, and a history of thyroid disease were significant predictors for both recurrence of AF and progression to PersAF.*
Chronic inflammation harbors a vulnerable substrate for atrial fibrillation (AF) recurrence after catheter ablation. However, whether the ABO blood types are associated with AF recurrence after catheter ablation is unknown. A total of 2106 AF patients (1552 men, 554 women) who underwent catheter ablation were enrolled retrospectively.
View Article and Find Full Text PDFBackground: Arrhythmia is a significant clinical modifier in COVID-19 patient outcomes. Currently, data on arrhythmia and ECG characteristics in COVID-19 from lower middle-income countries are limited.
Methods: COVID-19 was confirmed by polymerase chain reaction testing of a nasopharyngeal sample.
Background: The comprehensive surveillance for interval changes in signal-averaged P-wave (SAPW) after pulmonary vein isolation (PVI) remains lacking. We aimed to analyze the SAPW parameters before and after PVI and explored their link to the left atrial electrical properties.
Methods: Eighteen patients with paroxysmal atrial fibrillation receiving primary catheter ablation were enrolled.
Article Synopsis
- A study investigated the long-term cardiovascular outcomes of patients with typical and atypical atrial flutter (AFL) who underwent catheter ablation compared to those who received medical therapy without ablation.
- The study analyzed 3,784 AFL patients, finding that those who had catheter ablation experienced significantly lower risks of all-cause mortality, cardiovascular-related deaths, heart failure hospitalizations, and stroke.
- The results suggest that catheter ablation for AFL in patients without a history of atrial fibrillation leads to better long-term health outcomes.
Article Synopsis
- PDE-1 isoform inhibitors, specifically ITI-214, show promise for treating heart failure by affecting the heart's electrical activity, particularly in the pulmonary vein (PV), which often triggers atrial fibrillation.
- Using techniques like microelectrodes and patch clamps, the study assessed how ITI-214 impacts PV electrical function, revealing significant reductions in PV spontaneous beating rate and diastolic tension at higher concentrations.
- The results indicate that ITI-214 decreases specific ionic currents (late sodium current, L-type calcium current, and reverse sodium-calcium exchanger), suggesting that PDE-1 inhibition could be a novel therapeutic approach for managing atrial fibrillation and heart failure.
Introduction: The efficacy of stereotactic body radiation therapy (SBRT) as an alternative treatment for recurrent ventricular tachycardia (VT) is still unclear. This study aimed to report the outcome of SBRT in VT patients with nonischemic cardiomyopathy (NICM).
Methods: The determination of the target substrate for radiation was based on the combination of CMR results and electroanatomical mapping merged with the real-time CT scan image.
Background: Left atrial appendage (LAA) closure device is an alternative to anticoagulants for stroke prevention in selected atrial fibrillation (AF) patients. The LAA device implantation is safe with short period of learning curve. The standard implantation technique warrants a transesophageal echocardiography (TEE) guided and general anesthesia.
View Article and Find Full Text PDF