Mapping Oral health and Local Area Resources (MOLAR): protocol for a randomised controlled trial connecting emergency department patients with social and dental resources.

Introduction: There are substantial inequities in oral health access and outcomes in the USA, including by income and racial and ethnic identity. People with adverse social determinants of health (aSDoH), such as housing or food insecurity, are also more likely to have unmet dental needs. Many patients with dental problems present to the emergency department (ED), where minimal dental care or referral is usually available.

How Often Do Oral Maxillofacial Surgeons Lose Malpractice Cases and Why?

Purpose: Although oral maxillofacial surgeons (OMSs) carry high legal risk in malpractice lawsuits, data elucidating the reason behind those claims and their outcomes are scarce. The purpose of the present study was to characterize the trends, analyze the payouts, and determine the etiology of malpractice cases against OMSs.

Materials And Methods: A retrospective case series study was performed using the Westlaw database to access medical malpractice cases filed against OMSs from 1980 to 2017.

The Development of Dual-Degree Programs in Oral and Maxillofacial Surgery: Celebrating the 75th Anniversary of the Journal of Oral and Maxillofacial Surgery and the 100th Anniversary of Our Specialty.

The concept and history of dual-degree residency education and training are reviewed.

Massachusetts needs a PGY-1 option for licensure.

The American Dental Association (ADA) House of Delegates voted to eliminate live patient clinical exams in the year 2000. Canadian dental graduates take an objective structured clinical examination (OSCE) for licensure. Several states have changed their dental practice acts to permit licensure by mentored experience of a general residency or specialty Dental students have led the fight, with some results, to eliminate a practice--live patient exams--that perpetuates unprofessional and potentially illegal activity.

A faculty group practice-driven credentialing and privileging infrastructure in a school of dental medicine.

Credentialing and assigning clinical privileges are well-established practices in institutions that need to verify a clinician's ability to provide direct patient care services. The credentialing process verifies a provider's credentials to practice his or her profession, while privileging authorizes the individual to perform enumerated procedures within a specific scope of practice. All clinical faculty members at Harvard School of Dental Medicine (HSDM) practice in the Faculty Group Practice (FGP).

Using ultrasound to visualize the lingual nerve.

Purpose: The purpose of this study was to assess the effectiveness of ultrasonography in visualizing the lingual nerve, calculating its distance from the lingual cortex at the area of the third molar, and in detecting injuries.

Materials And Methods: Using a standardized protocol, lingual nerve dissections were performed in Yorkshire pig cadaver heads. After nerve isolation was confirmed, the nerve was left intact, fully transected, or partially transected.

Functional subtyping of muscarinic receptors on canine esophageal mucosa.

Serosal addition of muscarinic agonists elicited rapid changes in electrical parameters across the isolated canine esophageal epithelium set up in vitro. Both carbachol and the M1-selective agonist, McNeil A343 (McN), increased transmucosal potential differences (PDs), decreased transmucosal resistances (R), and increased short-circuit currents (Isc). Carbachol was more potent and more effective than McN.

The eosinophil as a cellular source of transforming growth factor alpha in healing cutaneous wounds.

Epidermal growth factor (EGF) and transforming growth factor-alpha (TGF-alpha) are known to promote the healing of epithelial wounds. Eosinophils are present in healing wounds and have recently been shown to be capable of producing TGF-alpha. This investigation was done to determine if eosinophils infiltrated into healing wounds are capable of expressing this cytokine.

Luminal responses to bradykinin on the isolated canine tracheal epithelium: effects of bradykinin antagonists.

We have tested the ability of several B2 antagonists on the responses of the open-circuited isolated canine tracheal epithelium to the luminal addition of Bradykinin (BK), Lys-BK, and substance P (SP). All three peptides produced biphasic changes in transmural potential difference (PD), an initial decrease (dip) followed by an increase (rise). The B2 antagonists D-Arg0 [Hyp3,Thi5,8,D-Phe7]BK (B5630) reversibly inhibited both the dips and the rise with IC50 values of 2.

A rapid method to determine proliferation patterns of normal and malignant tissues by H3 mRNA in situ hybridization.

A general method applicable for the determination of any mammalian tissue's proliferative pattern is described. This method determines the cellular mRNA level of a proliferation-dependent gene, histone H3, by in situ hybridization. The cell-cycle S-phase-specific expression of this highly conserved ubiquitous cellular gene, and the lack of it in resting cells, permits the unambiguous identification of cycling cells in any tissues, normal or diseased.

TGF-alpha and EGF-receptor mRNAs in human oral cancers.

Transforming growth factor alpha (TGF-alpha) and epidermal growth factor receptor (EGFR) have been shown to be present in most squamous cell carcinomas. Using the Syrian hamster oral cancer model, we have recently demonstrated the consistent presence of TGF-alpha and EGFR mRNAs in chemically transformed hamster oral keratinocytes. We now present evidence that in human oral cancer (in vivo and in vitro), TGF-alpha and EGFR mRNAs can also be consistently detected.