Background: Calcineurin inhibitors such as cyclosporine are effective in preventing rejection in recipients of solid organ transplants. Unfortunately, the prolonged use of calcineurin inhibitors may result in progressive renal injury.
Methods: We studied the renal function of 15 pediatric heart transplant recipients who were taking calcineurin inhibitors.
Background: With the introduction of atypical neuroleptic medications into the marketplace, the use of conventional neuroleptics has fallen, attendant with the perception of a more favorable side-effect profile for the atypical neuroleptics.
Objective: The purpose of this study was to determine the risk of tardive dyskinesia (TD) associated with atypical and conventional neuroleptics.
Methods: Subjects were adult users of the Veterans Administration Puget Sound Health Care System (VA-PSHCS) who received >or=1 prescription for neuroleptic medications during the study period.