Although personality is thought to be 50% heritable, consensus has not been reached about the specific genes involved, interest in genes affecting personality and behavior continues because of the linkage of personality traits with both physical and mental illness. One hundred and twenty years of study of the ABO blood types and the genes causing them has led to more precise assignment of genotype-phenotype linkage. Countries like Japan and Korea with 100 years history of study of ABO blood groups and personality as well as other countries have published research with no consensus.
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November 2020
Maternal mortality rate has increased in the United States over the past 30 years from 16 deaths per 100,000 births to 28 deaths per 100,000 births while the rest of the world is experiencing declining rates. Increasing obesity and c-section rates in the US have been cited as contributing factors needing remediation, and because of the two to three fold difference in maternal mortality rates in non-Hispanic black women compared to white women, inequality and implicit racial bias has been targeted as well for remediation. Using an epidemiologic approach, a hypothesis here brought to bear is that US immigration policy changes over the past 50 years have brought changes in the gene pool that have caused increasing obstetric hemorrhage and other causes of maternal death.
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November 2013
Antisocial personality traits are an important topic for research. The societal cost of these behaviors encourages efforts at a better understanding of central nervous system causes. Catecholamine genes are being studied to facilitate this understanding, and some tentative findings are being reached about several of these genes.
View Article and Find Full Text PDFPersonality trait research has shown associations with many genes, prominently those of the catecholamine metabolism such as dopamine beta hydroxylase (DBH), catechol-O-methyltransferase (COMT), and monoamine oxidase A (MAOA). Because DBH gene is in linkage disequilibrium with ABO gene, there is reason to think that other catecholamine genes using the same substrate as DBH may also have associations with ABO blood groups, and this paper demonstrates how this may be so. Reasons include similarities in hapmap population frequency distributions, similarities in illness risks between ABO blood groups and DBH activities as well as between ABO blood groups and COMT activities and between ABO blood groups and MAOA activities.
View Article and Find Full Text PDFIllness is strongly influenced by genetics. Personality traits are influenced by genetics and have linkages with, at least, affective illness. Because genetics influences both personality and illness, we studied by literature review the genes that illness and personality traits share and, by office assessment, our patient population's illnesses and personality traits.
View Article and Find Full Text PDFPrimary appendiceal carcinoma is extremely rare and is found in approximately 1% of appendectomy specimens. When cancer is present, the most frequent histology is mucinous adenocarcinoma. Neoplasms of the appendix that secrete mucin such as adenocarcinoma may rupture, leading to intraperitoneal seeding of the peritoneum and producing the clinical picture of pseudomyxoma peritonei (PMP).
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