Publications by authors named "Donna Ertz"
Int J Mol Sci
November 2017
Article Synopsis
- The study analyzed the prognostic score from the Memorial Sloan Kettering Cancer Center (MSKCC) in relation to blood mRNA expression in metastatic clear cell renal cell carcinoma (mCCRCC) patients.
- In a discovery phase with 19 patients, researchers identified 18 candidate genes associated with overall survival through RNA sequencing, and further validated their findings in an independent group of 47 patients using a customized probeset.
- The analysis revealed that two specific genes significantly improved survival predictions alongside the MSKCC score, indicating that whole blood mRNA profiling could enhance prognostic assessments for mCCRCC and warrants further research.
