Sodium-Glucose Cotransporter 2 Inhibitors Significantly Lower the Cardiac Electrophysiological Balance Index in Type 2 Diabetes Patients.

Objective: Sodium-glucose cotransporter 2 (SGLT2) inhibitors, a novel group of oral antidiabetic drugs, have demonstrated cardioprotective benefits and positive metabolic effects in patients with diabetes mellitus (DM). The cardiac electrophysiological balance index (ICEB) is an eletrocardiographic ratio that provides information about the equilibrium between left ventricular depolarization and repolarization duration, offering valuable insights into the predisposition to ventricular arrhythmias. The aim of this study is to analyze the potential impact of SGLT2 inhibitors on ICEB.

The relationship between serum Lumican levels and myocardial fibrosis in patients with hypertrophic cardiomyopathy.

Objective: Hypertrophic cardiomyopathy (HCM) is the leading cause of sudden cardiac death in young individuals. Lumican, is an indicator of fibrosis. We aimed to evaluate the relation between serum Lumican levels and presence and extent of myocardial fibrosis in HCM.

Predictors of stages of adoption of colorectal cancer screening among adults attending primary healthcare centers in Turkey.

Background: Despite the proven effectiveness of colorectal cancer (CRC) screening in reducing mortality, adherence rates for fecal occult blood testing (FOBT) and colonoscopy remain low among Turkish adults. This study aimed to assess the stages of adoption of CRC screening behaviors, identify the factors influencing adoption, and examine the perceived benefits and barriers to screening.

Methods: A cross-sectional study was conducted in Istanbul's Anatolian region from May to June 2022, involving 498 adults aged 50-70 years.

Fluctuation in body composition and urine specific gravity of Turkish wrestlers in a top-level official wrestling competition.

Purpose: This research aimed to examine the fluctuations in body composition and Urine-Specific Gravity (U) of elite wrestlers in a high-level official wrestling competition.

Method: Thirty-one wrestlers in the Türkiye Senior Greco-Romen Wrestling national team participated in this research. Wrestlers were divided into weight loss and non-weight loss groups, and changes in their body composition and U were measured at three different times (beginning of the camp, weigh-in, and before the competition).

The outcomes of the 5 mm versus 11 mm primary trocar in gynecologic surgery - randomised study.

Objectives: To compare the effects of using 11 mm trocar and 5 mm trocar as primary ports on postoperative pain in benign gynecological laparoscopic surgeries.

Material And Methods: The patients were divided into two groups as the primary port, group I (5 mm trocar) and group II (11 mm trocar) by block randomization.

Results: In the 5 mm trocar group, postoperative pain score and need for analgesia were less in level I and level II operations.

Peripheral Venous Pressure-Guided Decongestive Therapy in Heart Failure 2 (PERIPHERAL-HF2).

Congestive symptoms are the primary cause of hospitalizations in heart failure (HF), and diuretics remain the cornerstone of their management. However, clinical practice varies widely due to a lack of a reliable measure of congestion guiding diuretic use. Consequently, many HF patients are discharged prematurely without adequate decongestion, leading to increased readmissions and mortality.

Management of Canine Leishmaniasis and the Treatment Trends of Veterinarians in Aegean Region of Türkiye: A Questionnaire-based Survey.

Objective: Canine leishmaniasis (CanL) is an important veterinary and public health problem in Mediterranean countries. Although CanL and vector sandflies are widespread in the study area, there are no standardized diagnostic and treatment methods followed by private clinics. This study aimed to survey (i) the treatment, diagnosis, and control measures preferred by veterinarians, (ii) compare the differences in the first-step diagnostic tests applied, and (iii) identify differences in the guidance for CanL.

A new technique for stress urinary incontinence without using vaginal mesh.

Stress urinary incontinence (SUI) is a fairly common disease among women. Synthetic meshes are frequently used in midurethral sling procedures due to the high long-term success rates. Because of the publications about vaginal mesh complications in recent years, urogynecologists are turning to techniques without mesh.

Interpretation of pseudothrombocytopenia using platelet histograms and flags in a hematology autoanalyzer in a healthy child: a case report.

Background: Pseudothrombocytopenia is a spurious thrombocytopenia caused mostly by ethylenediaminetetraacetic acid (EDTA) use, and if detected early, unnecessary testing and treatment can be avoided. We present pseudothrombocytopenia caused by EDTA and citrate in an asymptomatic healthy child, as well as the value of using peripheral blood smear, platelet histogram, and flag data.

Case: A previously healthy 13-year-old girl with thrombocytopenia who developed tonsillitis 12 days previously was referred to our hematology department.

The uric acid/albumin ratio might be a better indicator for predicting repeat revascularization in young patients with acute coronary syndrome: Beyond inflammatory biomarkers.

Background: Despite advancements in percutaneous and surgical revascularization techniques, nearly 20% of patients who undergo myocardial revascularization need repeat revascularization. Recently, identified as a prognostication factor for adverse cardiovascular events, the uric acid/albumin ratio (UAR) serves as a new marker for assessing inflammation and oxidative stress. Our objective was to investigate the association between UAR levels and repeat revascularization in young patients with acute coronary syndrome (ACS).

Human gender estimation from CT images of skull using deep feature selection and feature fusion.

This research endeavors to prognosticate gender by harnessing the potential of skull computed tomography (CT) images, given the seminal role of gender identification in the realm of identification. The study encompasses a corpus of CT images of cranial structures derived from 218 male and 203 female subjects, constituting a total cohort of 421 individuals within the age bracket of 25 to 65 years. Employing deep learning, a prominent subset of machine learning algorithms, the study deploys convolutional neural network (CNN) models to excavate profound attributes inherent in the skull CT images.

The role of morphometric characteristics in predicting 20-meter sprint performance through machine learning.

The aim of this study was to test the morphometric features affecting 20-m sprint performance in children at the first level of primary education using machine learning (ML) algorithms. In this study, 130 male and 152 female volunteers aged between 6 and 11 years were included. After obtaining demographic information of the participants, skinfold thickness, diameter and circumference measurements, and 20-m sprint performance were determined.

Innovative Cancer Follow-Up with Telehealth: A New Method for Oncology Nurses.

Objectives: Telenavigation (TN) is an innovative cancer follow-up method for oncology nurses. Little is known about the effectiveness of tele-navigation on cancer patients. This study investigated the opinions of healthcare providers (HCPs) and colorectal cancer patients' experience regarding patient follow-up with TN.

The effect of interventions in vaginal birth on fear of childbirth: A multicentre study.

Aim: This cross-sectional multicentre study aimed to determine the effect of interventions during vaginal birth for fear of childbirth.

Methods: In this cross-sectional and analytical study, 852 women who had a vaginal birth between 2019 and 2020 were enrolled. Data were collected using the Descriptive Questionnaire and Wijma Birth Expectation/Experience Scale Version B.

Total vNOTES hysterectomy versus conventional total laparoscopic hysterectomy in virgin transgender men.

Background And Aim: Comparison of the applicability, safety, and surgical outcomes of total vaginal NOTES hysterectomy (TVNH) using natural orifice transluminal endoscopic surgery, which is considered a natural orifice surgery for hysterectomy with bilateral salpingo-oophorectomy (HBSO) in virgin transgender men, with conventional total laparoscopic hysterectomy (TLH).

Material And Methods: A retrospective cohort study was conducted between 2019 and 2021. The results of transgender male individuals who underwent HBSO operations using TVNH ( = 21) were compared with those who underwent operations using TLH ( = 62).

Role of Cardiac Risk Scores in Clinical Use to Predict Outcomes of Acute Ischemic Stroke.

Introduction: Acute coronary syndromes and ischemic stroke have similar risk factors. Risk scores help to identify disease severity in both diseases. We aimed to evaluate if HEART (History, ECG, Age, Risk factors, and Troponin) score could predict re-hospitalization, recurrent cardiac/cerebrovascular events risk, and mortality within 1-year follow-up in patients presenting with acute ischemic stroke.

The association between hemogram parameters and the development of contrast-induced nephropathy in patients presenting with non-ST-elevation myocardial infarction.

Objectives: Hemogram parameters such as mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLr), red cell distribution width and platelet distribution width are widely used inflammatory indicators to assess prognosis in various cardiovascular diseases. In this study, we aimed to investigate the role of hemogram parameters to predict the development of contrast-induced nephropathy (CIN) in patients presenting with non-ST segment elevation myocardial infarction (non-STEMI) and treated with percutaneous coronary intervention (PCI).

Methods: All pateints who underwent PCI with a diagnosis of non-STEMI between 2017 and 2020 in our center were included retrospectively in this study.

LAMB2 gene: broad clinical spectrum in Pierson syndrome.

Pierson syndrome (PS) is a rare autosomal recessive disease, characterized by congenital nephrotic syndrome (CNS), and ocular and neurologic abnormalities. In affected cases, there is abnormal b-2 laminin which is compound of the several basement membranes caused by inherited mutations in the LAMB2 gene. Although patients have mutations in the same gene, the phenotype is highly variable.

Can GRACE Risk Score Predict Mortality and the Need for Thrombolytic Treatment in Acute Pulmonary Embolism?

Acute coronary syndrome and pulmonary embolism (PE) are clinical entities sharing similar presentation and risk factors. Risk scores and indexes help to identify disease severity in both diseases. In this study, we aimed to evaluate if the Global Registry of Acute Coronary Events (GRACE) risk score could predict 30-day mortality and the need for thrombolytic treatment in patients with acute PE.

Is dynamic change in mean platelet volume related with composite endpoint development after transcatheter aortic valve replacement?

Aortic valve stenosis (AS) is the most common valvular disease, and surgical or transcatheter aortic valve replacement (TAVR) are the treatment options. Diminish in platelet production or dysfunction may occur due to shear stress, advanced age, and other coexisting diseases in AS patients. Bleeding is one of the complications of TAVR and associated with increased mortality.

Positive blood pressure response may predict the recovery of renal function after transcatheter aortic valve implantation.

Objective: Transcatheter aortic valve implantation (TAVI) may ameliorate renal function and increase blood pressure (BP). We aimed to investigate the association between increased BP and improved renal function (IRF) after TAVI.

Methods: A total of 176 patients who had undergone TAVI were evaluated retrospectively.

Effects of Androgens on the Thickness of Retinal Layers in Transgender Men and in Women with Polycystic Ovarian Syndrome.

Purpose: This study aimed to evaluate the relationship between androgens and the retinal thickness by comparing the macular thickness (MT), retinal nerve fiber layer (RNFL), and ganglion cell complex (GCC) thickness of female-to-male transgender men (TGM), women with polycystic ovary syndrome (PCOS), and cisgender women (CW).

Methods: Thirty-four eyes of 34 TGM, 34 eyes of 34 women with PCOS, and 45 eyes of 45 CW were evaluated by optical coherence tomography. One-way analysis of variance and body mass index (BMI)-adjusted one-way analysis of covariance were conducted to test the differences between groups for statistical evaluation.