Publications by authors named "Donia Lejri"
Article Synopsis
- Invasive lobular carcinoma (ILC) is identified as a distinct subtype of breast cancer, primarily associated with CDH1 mutations, while data on its connection with BRCA1/2 and TP53 mutations remains limited.
- A study from 1992 to 2016 analyzed breast cancer cases (n=3469), revealing a significantly lower proportion of ILC in BRCA1 and TP53 mutation carriers compared to other groups.
- The findings suggest that BRCA1 and TP53 likely do not predispose individuals to ILC, providing important insights for genetic counseling in ILC patients.
