Publications by authors named "Dongyun Jung"

is a common environmental pathogen associated with clinical mastitis (CM) in dairy cattle. There is an interest in optimizing the udder microbiome to increase the resistance of dairy cattle to CM; however, the details of which members of the healthy udder microbiome may play a role in antagonizing are unknown. In this study, we characterized the bacterial community composition in raw milk collected from quarters of lactating Holstein dairy cows that developed CM during lactation, including milk from both healthy and diseased quarters ( = 1,172).

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Article Synopsis
  • Members of a specific species complex are known to be common pathogens causing clinical mastitis in cattle and also lead to infections in humans.
  • The text presents 148 draft genome assemblies and annotations related to these species complex members.
  • The data includes samples from both bovine and human hosts specifically in Canada.
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Background: Staphylococcus aureus is a common cause of clinical mastitis (CM) in dairy cattle. Optimizing the bovine mammary gland microbiota to resist S. aureus colonization is a growing area of research.

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is a major etiological agent of clinical and subclinical bovine mastitis. The versatile and adaptative evolutionary strategies of this bacterium have challenged mastitis control and prevention globally, and the high incidence of mastitis increases concerns about antimicrobial resistance (AMR) and zoonosis. This study aims to describe the evolutionary relationship between bovine intramammary infection (IMI)-associated and human pathogenic and further elucidate the specific genetic composition that leads to the emergence of successful bovine IMI-associated lineages.

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Antimicrobial resistance is one of the most serious threats to medical science. Food supply is recognized as a potential source of resistant bacteria, leading to the development of surveillance programs targeting primarily poultry, pork, and beef. These programs are limited in scope, not only in the commodities tested, but also in the organisms targeted (, , and ); consequently, neither the breadth of food products available nor the organisms that may harbour clinically relevant and (or) mobile resistance genes are identified.

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Staphylococcus aureus is one of the main pathogens leading to both clinical and subclinical bovine mastitis in dairy cattle. Prediction of disease evolution based on the characteristics of Staph. aureus isolates that cause intramammary infections and understanding the host-pathogen interactions may improve management of mastitis in dairy herds.

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Article Synopsis
  • - Bovine mastitis, a prevalent infectious disease in dairy cattle, poses economic challenges and requires ongoing monitoring of antimicrobial resistance (AMR) for both animal and public health.
  • - A study analyzed 113 E. coli isolates from mastitis cases in Canada to assess resistance to antibiotics and heavy metals, discovering that 32 isolates were resistant to antibiotics and 107 to heavy metals, with varying biofilm production and virulence factors present.
  • - The findings highlight the prevalent AMR in E. coli from bovine mastitis, indicating that single-mode antimicrobials may not effectively combat bacteria with multiple resistance mechanisms.
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  • Environmental bovine mastitis, caused by mammary pathogenic Escherichia coli (MPEC), leads to significant economic losses in the dairy industry, with ongoing debate about whether MPEC is a distinct pathotype or an opportunistic infection.
  • A genomic analysis of 113 MPEC isolates from clinical cases and 100 bovine commensal isolates revealed that while MPEC and commensal strains grouped by genetic similarities, they did not cluster based on their pathogenicity.
  • The study identified nine unique genes in the MPEC genome associated with nutrient metabolism and virulence factors, which could be important for further research on the disease's underlying mechanisms.
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is one of the most common etiological agents responsible for clinical bovine mastitis. Here, we report the draft genome sequences and annotations of 113 strains that were isolated from Holstein cows with intramammary infections in Canada.

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Current food production faces a tremendous challenge due to the growing human population. The global population is estimated to reach 9 billion by 2050 with 70% more food being required. Safe food is an important dimension of food security, and food traceability across the supply chain is a key component of this.

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is one of the most common etiological agents responsible for contagious bovine mastitis. Here, we report the draft whole-genome sequences, with annotations, of 27 strains and 3 species strains that were isolated from Holstein cows with intramammary infection in Canada.

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The role of plant-based foods in the epidemiology of antimicrobial resistance has been inadequately studied. In this investigation, resistant organisms from vegetables, fruits and spices imported into Canada were identified and characterized. A total of 143 products imported from primarily Asian and African countries were purchased from international markets in Saskatoon, Saskatchewan.

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This study revealed the antimicrobial properties of actinonin against major foodborne pathogens, O157:H7, , Typhimurium, and . Among them, actinonin caused growth defect in Typhimurium and . Minimal inhibitory concentration (MIC) values of actinonin were determined by broth microdilution methods.

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