Review: Application of Bionic-Structured Materials in Solid-State Electrolytes for High-Performance Lithium Metal Batteries.

Solid-state lithium metal batteries (SSLMBs) have gained significant attention in energy storage research due to their high energy density and significantly improved safety. But there are still certain problems with lithium dendrite growth, interface stability, and room-temperature practicality. Nature continually inspires human development and intricate design strategies to achieve optimal structural applications.

An Artificial Neural Network Based on Oxide Synaptic Transistor for Accurate and Robust Image Recognition.

Synaptic transistors with low-temperature, solution-processed dielectric films have demonstrated programmable conductance, and therefore potential applications in hardware artificial neural networks for recognizing noisy images. Here, we engineered AlO/InO synaptic transistors via a solution process to instantiate neural networks. The transistors show long-term potentiation under appropriate gate voltage pulses.

The synthesis of gold nanoclusters with high stability and their application in fluorometric detection for Hg and cell imaging.

Sensing Hg is significant to protecting human health and environmental ecosystems, for its toxicity and genotoxicity. Here, highly stable fluorescent folic acid (FA)-protected Au nanoclusters (FA-AuNCs) were synthesized by optimizing the reactive parameters with high quantum yield of 34.7%.

High crystallinity Sn crystals on Ni foam: an ideal bimetallic catalyst for the electroreduction of carbon dioxide to syngas.

The investigation of highly efficient catalysts for the electrochemical reduction of carbon dioxide (ER-CO) is the most critical challenge to commercialize conversion and utilization of CO. Herein we propose a new and very promising catalyst, high crystallinity Sn crystals on Ni foam (Sn@f-Ni), for the electroreduction reaction of CO in potassium bicarbonate aqueous solution. The catalyst is fabricated on a pretreated Ni foam substrate through a galvanostatic electrodeposition strategy.

A Removable Artificial Cell Wall for Withstanding Ciprofloxacin.

The pollution of antibiotics in aquaculture environment is increasingly serious, and excessive antibiotics will kill the probiotics in aquaculture feed. How to improve the viability of probiotics in the antibiotics-contaminated environment is of significance. In this study, a new strategy for protecting Saccharomyces cerevisiae cells in situ against antibiotics is constructed based on cell surface engineering technology by putting on wearable protective layers for cells.

Enzyme-Modulated Anaerobic Encapsulation of Chlorella Cells Allows Switching from O to H Production.

Single-cell encapsulation has become an effective strategy in cell surface engineering; however, the construction of cell wall-like layers that allow the switching of the inherent functionality of the engineered cell is still rare. In this study, we show a universal way to create an enzyme-modulated oxygen-consuming sandwich-like layer by using polydopamine, laccase, and tannic acid as building blocks, which then could generate an anaerobic microenvironment around the cell. This layer protected the encapsulated C.

Gypenoside inhibits RANKL-induced osteoclastogenesis by regulating NF-κB, AKT, and MAPK signaling pathways.

Gypenoside (GP) is one of the most pharmacologically active components in Gynostemma pentaphyllum and possesses neuroprotective, anticancer, anti-oxidant, anti-inflammatory, anti-diabetic, and anti-osteoarthritis effects. However, the involvement of GP the osteoclast differentiation has not yet been investigated. In the present study, we examined the effect of GP on receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation.

Construction of biological hybrid microcapsules with defined permeability towards programmed release of biomacromolecules.

An effective method to modulate the permeability of microcapsules on demand based on a "self-sacrificing" strategy was demonstrated, which then realized a programmed release of the corresponding loaded biomacromolecules.

Knockdown of IQGAP1 inhibits proliferation and epithelial-mesenchymal transition by Wnt/β-catenin pathway in thyroid cancer.

Background: Thyroid cancer is the most common endocrine malignant disease with a high incidence rate. The expression of IQGAP1 is upregulated in various cancers, including thyroid cancer. However, the role and underlying mechanism of IQGAP1 in thyroid cancer are still not clear.

Silencing of A-Kinase Anchor Protein 4 (AKAP4) Inhibits Proliferation and Progression of Thyroid Cancer.

A-kinase anchor protein 4 (AKAP4), a member of the A-kinase anchor family of proteins, plays a role in tumor development and progression. However, its expression pattern and function in human thyroid cancer remain obscure. Here we examined AKAP4 expression in thyroid cancer cell lines as well as the effects of AKAP4 on the proliferation and metastasis of thyroid cancer cells.

Bio-inspired engineering proteinosomes with a cell-wall-like protective shell by self-assembly of a metal-chelated complex.

A cell-wall-like shell is constructed around proteinosomes by coordination complexes of tannic acid and Fe, which endows the engineered proteinosomes with an enhanced Young's modulus of the membrane, protease resistant ability, EDTA-mediated release of loaded DNA, and electrostatic gated encapsulated enzyme activity, as well as antioxidant capacity.

Establishment of pancreatic cancer stem cells by flow cytometry and their biological characteristics.

To investigate the method of separating human pancreatic cancer stem cells by Hoechst 33342 labeled flow cytometry and to analyze the biological properties of pancreatic cancer stem cells. The human pancreatic cancer cell line PC-3 was divided into SP and non-SP cells by flow cytometry. The number of two cell clone spheres and nude mice tumor formation rates were compared by cultivating in serum-free medium; The expression of CD133, Nestin mRNA and protein was analyzed by real-time fluorescence quantitative PCR and Western blot; The expression of two cell drug resistance genes (MDR1, ABCG2, ABCA2 and MRP1) was analyzed by real time fluorescent quantitative PCR.

MiR-200 Regulates Epithelial-Mesenchymal Transition in Anaplastic Thyroid Cancer via EGF/EGFR Signaling.

This study was set to study the molecular mechanism underlying how miR-200 regulates EGF/EGFR signaling to involve in epithelial-mesenchymal transition (EMT) in anaplastic thyroid cancer (ATC) cells. Loss-of-function experiments of EGFR silencing by siRNA transfection was performed. Transfection of pre-miR-200s or anti-miR-200s was used to increase or decrease miR-200 transcripts.

Folic acid functionalized silver nanoparticles with sensitivity and selectivity colorimetric and fluorescent detection for Hg2+ and efficient catalysis.

In this research, folic acid functionalized silver nanoparticles (FA-AgNPs) were selected as a colorimetric and a 'turn on' fluorescent sensor for detecting Hg(2+). After being added into Hg(2+), AgNPs can emit stable fluorescence at 440 nm when the excitation wavelength is selected at 275 nm. The absorbance and fluorescence of the FA-AgNPs could reflect the concentration of the Hg(2+) ions.

Fluorescent detection of TNT and 4-nitrophenol by BSA Au nanoclusters.

Rapid and sensitive detection of 2,4,6-trinitrotoluene (TNT) and 4-nitrophenol (4-NP) has attracted considerable attention due to their wide applications as nitroaromatic explosive materials. A novel fluorescence method for TNT and 4-NP based on bovine serum albumin functionalized fluorescent gold nanoclusters (BSA Au-NCs) has been developed. The detection probe BSA Au-NCs can be used as a fluorescent probe for the sensitive and selective detection of TNT and 4-NP simultaneously.