Publications by authors named "Dongyuan Qin"

Background: Ulcerative colitis (UC) is a significant inflammatory bowel disease (IBD) that typically arises from chronic inflammation of the intestinal tract. Report suggest that anti-inflammatory drug plays a crucial role in the protection of UC. The recent study demonstrated that columbianadin has a protective effect against UC induced by dextran sulfate sodium (DSS) in rats through the modulation of HO-1/Nrf2 and TLR4-NF-κB signaling pathways.

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Article Synopsis
  • The text discusses an autosomal recessive disorder related to epilepsy caused by mutations in the WW-containing oxidoreductase gene, leading to severe seizures and developmental issues in infants.
  • A case study of a 5-month-old boy showcases intractable seizures, developmental delays, and a newly identified mutation that was inherited from his healthy parents.
  • The findings highlight the importance of discovering new gene variants, which could improve the understanding and treatment options for related disorders.
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Background: Chronic gastritis affects more than half of the global population to varying extents.

Objectives: This study aimed to investigate the knowledge, attitude, and practice (KAP) of patients admitted to the gastroenterology department in the Shanxi region concerning chronic gastritis.

Methods: This study was conducted in Shanxi between April and July 2023.

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The labeling-free and immobilization-free homogeneous aptamer sensor offers advantages including simple operation, low cost, and high sensitivity, demonstrating great potential in rapid detection of tumor biomarkers in biological samples. In this work, a labeling-free and immobilization-free homogeneous aptamer sensor was conveniently fabricated by combining size exclusion and charge-selective penetration of a nanochannel-modified electrode and two-dimensional (2D) nanorecognition probe which can realize selective and highly sensitive detection of alpha-fetoprotein (AFP) in serum. Vertically ordered mesoporous silica film (VMSF) with ultra-small, uniform, and vertically aligned nanochannels was easily grown on the simple, low-cost, and disposable indium tin oxide (ITO) electrode.

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