Post-Ortho-K Corneal Epithelium Changes in Myopic Eyes.

The study is aimed at evaluating corneal epithelial thickness changes associated with overnight orthokeratology (ortho-K). In this retrospective study, epithelial thickness was measured using optical coherence tomography (OCT) before and after 1 day, 1 week, 1 month, and 3 months ortho-K nightly lens wear. Compared with pre-orthokeratology measurements, central (2 mm) corneal epithelium thickness was significantly reduced at 1 day, 1 week, 1 month, and 3 months with ortho-K ( < 0.

Air pollutant particulate matter 2.5 induces dry eye syndrome in mice.

In this study, we explored the effects of particulate matter 2.5 (PM) eye drops on the ocular surface structure and tear function in mice and established a novel animal model for dry eye research. We found that, following treatment with PM, the tear volume and, the tear film break-up time showed statistical differences at each time point (P < 0.

Retinal nerve fiber layer (RNFL) integrity and its relations to retinal microvasculature and microcirculation in myopic eyes.

Background: The aim was to determine retinal nerve fiber layer function and its relations to retinal microvasculature and microcirculation in patients with myopia.

Method: Polarization-sensitive optical coherence tomography (PS-OCT) was used to measure phase retardation per unit depth (PR/UD, proportional to the birefringence) of the retinal nerve fiber layer (RNFL). Optical coherence tomography angiography (OCTA) was used to measure macular vessel density analyzed using fractal analysis.

Age-Related Alterations in the Retinal Microvasculature, Microcirculation, and Microstructure.

Purpose: To characterize age-related alterations in the retinal microcirculation, microvascular network, and microstructure in healthy subjects.

Methods: Seventy-four healthy subjects aged from 18 to 82 years were recruited and divided into four age groups (G1 with age <35 years, G2 with age 35 ∼ 49 years, G3 with age 50 ∼ 64 years, and G4 with age ≥65 years). Custom ultra-high resolution optical coherence tomography (UHR-OCT) was used to acquire six intraretinal layers of the macula.

Evaluated Conjunctival Blood Flow Velocity in Daily Contact Lens Wearers.

Objective: This study examined conjunctival microvasculature development in long-term habitual contact lens (HCL) wearers after a night of sleep.

Methods: Twenty HCL wearers (15 women and 5 men, aged 28.6±6.

Retinal Microvascular Network and Microcirculation Assessments in High Myopia.

Purpose: To investigate the changes of the retinal microvascular network and microcirculation in high myopia.

Design: A cross-sectional, matched, comparative clinical study.

Participants: Twenty eyes of 20 subjects with nonpathological high myopia (28 ± 5 years of age) with a refractive error of -6.