Grating-Integrated Gold Nanograsses Encapsulated with ZIF-8: A Quantitative and Ultrasensitive Surface-Enhanced Raman Scattering Substrate.

We proposed and demonstrated highly sensitive hybrid surface-enhanced Raman scattering (SERS) substrates, which are grating-integrated gold nanograsses (GIGN) that are tip-selectively encapsulated by ZIF-8 nanospheres (GIGN/tip-ZIF). This unique structure is realized through the tip-selective modification of GIGN by polyvinylpyrrolidone (PVP), and then, the tips of the GIGN were encapsulated by ZIF-8 nanospheres. The ZIF-8 nanospheres can adsorb analyte molecules, resulting in the spatial overlap between the analyte molecules and the "hotspots" on the tips of GIGN.

Preparation, characterization, and biological activity of Cinnamomum cassia essential oil nano-emulsion.

To solve the problems of low bioavailability and unstable properties of Cinnamomum cassia Essential oil (CCEO), encapsulation technology was introduced as an effective means to improve its shortcomings. In this study, Cinnamomum cassia Essential oil nano-emulsion (CCEO-NE) was successfully synthesized by the oil-in-water method and characterized by standard analytical methods, including dynamic light scattering (DLS), Scanning electron microscopy (SEM), and Transmission electron microscopy (TEM). The results show that the synthesized CCEO is spherical, smooth in surface, and uniform in shape, with an average particle size of 221.

SlBES1 promotes tomato fruit softening through transcriptional inhibition of .

Fruit softening indicated by firmness determines the texture, transportability, and shelf life of tomato products. However, the regulatory mechanism underlying firmness formation in tomato fruit is poorly understood. Here, we report the regulatory role of SlBES1, an essential component of brassinosteroid hormone signaling, in tomato fruit softening.

Regulation of fruit ripening by the brassinosteroid biosynthetic gene via an ethylene-dependent pathway in tomato.

The essential role of ethylene in fruit ripening has been thoroughly studied. However, the involvement of brassinosteroids (BRs) in the regulation of fruit ripening and their relationship with the ethylene pathway are poorly understood. In the current study, we found that BRs were actively synthesized during tomato fruit ripening.

Chorea and the effectiveness of steroids in a patient with the syndrome of transient headache with neurologic deficits and cerebrospinal fluid lymphocytosis: a case report.

Background: The clinical manifestations of the transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis (HaNDL) syndrome are variable, and involuntary movements have not been reported. The etiology and treatment of the syndrome are not entirely clarified.

Case: A 25-year-old female presented with recurrent transient headache, involuntary movements (left upper extremity chorea) and paralysis.

Identification of a novel mutation in PLA2G6 gene and phenotypic heterogeneity analysis of PLA2G6-related neurodegeneration.

Introduction: This study reports a novel mutation site of the phospholipase A2 group VI (PLA2G6) gene, and analyzes the information of 67 previously published cases to elucidate PLA2G6 phenotype-genotype variations.

Methods: We collected clinical data and examined gene mutation sites from one Chinese patient with adult-onset ataxia and her family. Next-generation sequencing (NGS) and Sanger sequencing were used to verify possible mutations.

Comparative transcriptomics uncovers alternative splicing and molecular marker development in radish (Raphanus sativus L.).

Background: Alternative splicing (AS) plays important roles in gene expression and proteome diversity. Single nucleotide polymorphism (SNP) and insertion/deletion (InDel) are abundant polymorphisms and co-dominant inheritance markers, which have been widely used in germplasm identification, genetic mapping and marker-assisted selection in plants. So far, however, little information is available on utilization of AS events and development of SNP and InDel markers from transcriptome in radish.

Genome-Wide Characterization of the MADS-Box Gene Family in Radish ( L.) and Assessment of Its Roles in Flowering and Floral Organogenesis.

The MADS-box gene family is an important transcription factor (TF) family that is involved in various aspects of plant growth and development, especially flowering time and floral organogenesis. Although it has been reported in many plant species, the systematic identification and characterization of MADS-box TF family is still limited in radish ( L.).

Carbon dioxide (CO₂) ablation as a remedy for hepatocellular carcinoma.

Background/aims: The purpose of this research was to investigate the application of carbon dioxide (CO₂) ablation and determine if carbon dioxide plays a role in treating hepatocellular carcinoma.

Methodology: Twelve mice with subcutaneous xenografts of a hepatocellular cancer cell line were randomly separated into 2 groups. One group underwent CO₂ ablation with their liver tumor in vivo while the other group in vitro, respectively.