Glyphosate combined with TBBPA exposure decreased quality and flavor of common carp (Cyprinus carpio) involved inhibiting muscle growth and collagen synthesis.

Glyphosate (N-[phosphonomethyl] glycine, GLY) is the active ingredient of the most widely used commercialized herbicide, and its use increases the potential for co-occurrence with flame retardants such as Tetrabromobisphenol A (TBBPA), posing a threat to aquatic systems and food safety. Therefore, it is important to prioritize evaluating these two compounds' combined toxicity. However, only a few studies have analyzed the effects of pollutant mixing on fish from the perspectives of molecular and nutritional components.

Serum A20 level is associated with bone mineral density in male patients with type 2 diabetes mellitus.

Background: A20, also known as TNF-α-induced protein 3 (TNFAIP3), is a crucial negative regulator of inflammation and immune responses. Emerging evidence suggests that A20 is involved in the regulation of glucose metabolism and plays a significant role in bone metabolic diseases by inhibiting nuclear factor (NF)-κB activation. However, the potential relationship between serum A20 level and bone mineral density (BMD) in patients with type 2 diabetes mellitus (T2DM) has not been explored.

A Chinese drug-compatibility-based approach to purslane hydrogels for acute eczema therapy.

Purslane () with heat-clearing and detoxicating, anti-inflammatory and resolving swelling, relieving itching and astringing function, has remarkable efficacy for acute eczema. However, most of the clinical applications of purslane are freshly prepared decoction, not as easy to apply as cream, because the decoction is easy to breed bacteria and easy to oxidize. Here, based on the theory of Chinese medicines compatibility, we made a purslane-tannic acid hydrogel (PL-HATA) by simple methods under mild conditions to solve the drawbacks of easy oxidation and inconvenience of use of Purslane.

Regulation of ofloxacin resistance in strains causing calf diarrhea by quorum-sensing acyl-homoserine lactone signaling molecules.

is a major pathogen responsible for calf diarrhea. However, it has developed resistance to many antimicrobial drugs for their inappropriate usage. The bacterial quorum sensing system transmits information between bacteria, it's important in regulating bacterial virulence, drug and acid resistance and so on.

Increased hip fracture risk in the patients with type 2 diabetes mellitus is correlated with urine albumin-to-creatinine ratio (ACR) and diabetes duration in men.

Patients with type 2 diabetes mellitus (T2DM) have increased hip fracture risk. And the association between urine albumin to creatinine ratio (ACR) and an increased risk of hip fracture in patients with T2DM remains controversial. This study aimed to investigate the association between urinary ACR and hip fracture risk in postmenopausal women and aged men with T2DM.

Improved Kaempferol Solubility via Heptakis-O-(2-hydroxypropyl)-β-cyclodextrin Complexation: A Combined Spectroscopic and Theoretical Study.

Four cyclodextrins (CDs) including heptakis-O-(2-hydroxypropyl)-β-cyclodextrin (HP-β-CD), heptakis-O-(2,6-di-O-methyl)-β-cyclodextrin (DM-β-CD), β-cyclodextrin (β-CD), and γ-cyclodextrin (γ-CD) were evaluated for their ability to enhance the aqueous solubility of kaempferol (Kae). Phase solubility studies indicated that these four CDs can form 1:1 type complexes with Kae and that HP-β-CD demonstrated the most significant solubilizing effect on Kae. Among the CDs tested, HP-β-CD demonstrated the most significant solubilizing effect on Kae.

Asymmetrically Wettable, PET/PA6, Hollow, Segmented-Pie, Microfiber Nonwovens for a Synthetic Leather Base.

PET/PA6, hollow, segmented-pie, microfiber nonwovens (PET/PA6 HSMNs) play an important role in a microfiber, synthetic leather base. Most of the current PET/PA6 HSMNs generally lack in hygiene performance. Moreover, there is an urgent need for the asymmetric wettability of PET/PA6 HSMNs to ensure the comfort of clothing.

Characteristics of bone metabolism in the male patients with diabetic neuropathy.

Background: This study aimed to evaluate the characteristics of bone metabolism and fracture risk in the type 2 diabetes mellitus (T2DM) patients with distal symmetric polyneuropathy (DSPN).

Methods: A total of 198 T2DM individuals were recruited from January 2017 to December 2020. Patients with DSPN were evaluated by strict clinical and sensory thresholds.

Automatic Detection of Thyroid Nodule Characteristics From 2D Ultrasound Images.

Thyroid cancer is one of the common types of cancer worldwide, and Ultrasound (US) imaging is a modality normally used for thyroid cancer diagnostics. The American College of Radiology Thyroid Imaging Reporting and Data System (ACR TIRADS) has been widely adopted to identify and classify US image characteristics for thyroid nodules. This paper presents novel methods for detecting the characteristic descriptors derived from TIRADS.

The effect of yoga classes on the mental health of female college students.

Background: Mental health problems have become prominent among college students. The purpose of this study was to to explore the influence of yoga course on female college students' mental health.

Methods: Three hundred fifty-four female college students enrolled in Anhui University of Traditional Chinese Medicine in 2020 or 2021 were selected and divided into three groups according to whether they took PE courses and the content of PE courses: No physical education group (control group) (N.

TBBPA causes apoptosis in grass carp hepatocytes involving destroyed ER-mitochondrial function.

Tetrabromobisphenol A (TBBPA) is the most-produced brominated flame retardant, which can be found in various industrial and household products. Studies have shown that TBBPA has hepatotoxicity, and could pose a risk to aquatic animals. The endoplasmic reticulum (ER) and mitochondria are two important organelles that are highly dynamic in cells, the homeostasis and orchestrated interactions of which are crucial to maintaining cellular function.

Co-exposure of avermectin and imidacloprid induces DNA damage, pyroptosis, and immune dysfunction in epithelioma papulosum cyprini cells via ROS-mediated Keap1/Nrf2/TXNIP axis.

Pesticide mixtures can reduce pest resistance, however, their overuse severely threatens aquatic animal survival and public health. Avermectin (AVM) and imidacloprid (IMI) are potent insecticides often employed in agriculture. By inducing oxidative stress, these chemicals can induce cell death.

Programmable Complex Shape Changing of Polysiloxane Main-Chain Liquid Crystalline Elastomers.

Liquid crystal elastomers (LCEs) are shape-morphing materials whose large and reversible shape transformations are caused by the coupling between the mobile anisotropic properties of liquid crystal (LC) units and the rubber elastic of polymer networks. Their shape-changing behaviors under certain stimuli are largely directed by the LC orientation; therefore, various strategies have been developed to spatially modulate the LC alignments. However, most of these methods are limited as they require complex fabrication technologies or have intrinsic limitations in applicability.

Hydrophilic Modification of Polyester/Polyamide 6 Hollow Segmented Pie Microfiber Nonwovens by UV/TiO/HO.

Polyester/polyamide 6 hollow segmented pie bicomponent spunbond hydro-entangled microfiber nonwovens (PET/PA6) with a microfilament structure have recently emerged in many markets around the world due to their green, high-strength, and lightweight properties. However, PET/PA6 is highly hydrophobic, which inhibits its large-scale application at present. In order to enhance the hydrophilic performance of PET/PA6, many methods have been applied, but the effects are not obvious.

DNA Double-Strand Break-Related Competitive Endogenous RNA Network of Noncoding RNA in Bovine Cumulus Cells.

(1) Background: DNA double strand breaks (DSBs) are the most serious form of DNA damage that affects oocyte maturation and the physiological state of follicles and ovaries. Non-coding RNAs (ncRNAs) play a crucial role in DNA damage and repair. This study aims to analyze and establish the network of ncRNAs when DSB occurs and provide new ideas for next research on the mechanism of cumulus DSB.

caused disseminated infection diagnosed by metagenomic next-generation sequencing in an acute myeloid leukemia patient: A case report.

Background: Mucormycosis commonly occurs in immunosuppressed patients with hematological diseases, which can be life-threatening. However, many cases are often misdiagnosed due to lack of specific clinical manifestations. Additionally, the traditional blood culture or serological testing, with a high false-negative rate, is time-consuming.

New Insights into How Melatonin Ameliorates Bisphenol A-Induced Colon Damage: Inhibition of NADPH Oxidase.

Bisphenol A (BPA) is an endocrine disruptor, widely employed, and detected in many consumer products and food items. Oral intake poses a great threat to intestinal health. Melatonin (MT) stands out as an endogenous, dietary, and therapeutic molecule with potent antioxidant capacity.

Does off-farm employment contribute to chemical fertilizer reduction? New evidence from the main rice-producing area in Jilin Province, China.

Frequent transfer of rural labor to cities in developing countries significantly impacts agricultural production. However, whether off-farm employment can promote chemical fertilizer (CF) reduction is still controversial. This study incorporates business scale (BS) and fragmentation degree of arable land (FDAL) into the theoretical analysis framework, shedding light on regulating effects of arable land resource endowment in the process of off-farm employment which influences CF application under different BS and FDAL scenarios.

CiRS-187 regulates BMPR2 expression by targeting miR-187 in bovine cumulus cells treated with BMP15 and GDF9.

Circular RNAs (circRNAs) play vital roles in regulating biological processes. However, the contributions of circRNAs to BMPR2 regulation during follicle development remain unknown. In this study, we first verified the optimal conditions for BMP15 and GDF9 treatment in bovine cumulus cells.

Optical wavelength selective actuation of dye doped liquid crystalline elastomers by quasi-daylight.

We explore obtaining different photo responses of liquid crystalline elastomer (LCE) materials through modulating the optical wavelengths in order to promote the development of precise photocontrol on LCE actuators, and thus study the effect of light-absorbing dyes with different absorption bands on the selective actuation of LCE materials. The dye-doped LCEs were prepared by incorporating special visible absorber dyes into thiol-acrylate main chain LCE (MC-LCE) matrices. The dyes showed photo actuation performance to LCEs due to the photothermal effects.

Recent progress in performance optimization of Cu-SSZ-13 catalyst for selective catalytic reduction of NO .

Nitrogen oxides (NO ), which are the major gaseous pollutants emitted by mobile sources, especially diesel engines, contribute to many environmental issues and harm human health. Selective catalytic reduction of NO with NH (NH-SCR) is proved to be one of the most efficient techniques for reducing NO emission. Recently, Cu-SSZ-13 catalyst has been recognized as a promising candidate for NH-SCR catalyst for reducing diesel engine NO emissions due to its wide active temperature window and excellent hydrothermal stability.

FeO-Fused Magnetic Air Stone Prepared From Wasted Iron Slag Enhances Denitrification in a Biofilm Reactor by Increasing Electron Transfer Flow.

nFeO was prepared from waste iron slag and loaded onto air stone (named magnetic air stone or MAS in the following text). The main component of air stone is carborundum. To study the magnetic effects of MAS on denitrification, a biofilm reactor was built, and its microbial community structure and electron transfer in denitrification were analyzed.

LncRNA-m18as1 competitively binds with miR-18a-5p to regulate follicle-stimulating hormone secretion through the Smad2/3 pathway in rat primary pituitary cells.

Long noncoding RNAs (lncRNAs) are expressed in different species and different tissues, and perform different functions, but little is known about their involvement in the synthesis or secretion of follicle-stimulating hormone (FSH). In general, we have revealed lncRNA‍‒‍microRNA (miRNA)‍‒‍‍messenger RNA (mRNA) interactions that may play important roles in rat primary pituitary cells. In this study, a new lncRNA was identified for the first time.