Publications by authors named "Dongxia He"
Article Synopsis
- Vancomycin is a key antibiotic for treating MRSA infections, but its overuse has led to increased bacterial resistance, prompting this study to find better alternatives.
- The research analyzed data from 38 trials involving 6,281 patients, measuring clinical success rates and adverse reactions of various antibiotics, including linezolid and combinations of other drugs with vancomycin.
- Results indicated that linezolid and certain drug combinations outperformed vancomycin in treating MRSA infections, showing higher success rates and lower resistance, while also highlighting the risks of more side effects with some treatments.
Antibiotic resistance has emerged as a grave threat to global public health, leading to an increasing number of treatment failures. Antimicrobial peptides (AMPs) are widely regarded as potential substitutes for traditional antibiotics since they are less likely to induce resistance when used. A novel AMP named Brevinin-1BW (FLPLLAGLAASFLPTIFCKISRKC) was obtained by the Research Center of Molecular Medicine of Yunnan Province from the skin of the .
View Article and Find Full Text PDFGastrointestinal cancer is a common clinical malignant tumor disease that seriously endangers human health and lacks effective treatment methods. As part of the innate immune defense of many organisms, antimicrobial peptides not only have broad-spectrum antibacterial activity but also can specifically kill tumor cells. The positive charge of antimicrobial peptides under neutral conditions determines their high selectivity to tumor cells.
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