Publications by authors named "Dongwei Xie"
(1) BACKGROUND: Metabolic abnormalities and immune inflammation are key elements within pathogenesis of pulmonary arterial hypertension (PAH). And in PAH patients, aberrant glutamine metabolism has been observed; however, the function of glutaminase 1 (GLS1) in macrophage is still unknown. So we aims to investigate GLS1's impact upon macrophages in PAH.
View Article and Find Full Text PDFObjective: The aim of this study was to assess right atrial (RA) function, including RA phase strain, via speckle-tracking echocardiography (STE) in a cohort of systemic lupus erythematosus (SLE) patients with pulmonary arterial hypertension (PAH) and in particular to explore the relationship between RA phase strain and the occurrence of cardiovascular events.
Methods: STE analyses of RA function were evaluated in patients with SLE-PAH and in 33 healthy control subjects. Clinical associations, serum biomarkers, echocardiographic data, survival times, and adverse cardiovascular events were evaluated.
Article Synopsis
- Excessive soil salinity negatively affects crop growth, especially during seed germination, which is particularly sensitive to salt stress, leading to low germination rates in okra seeds.
- A genome-wide association study (GWAS) analyzed 180 okra accessions using over 20 million SNP markers under varying salt conditions, identifying 511 significant SNP loci, including key loci on chromosomes 44 and 59 that influence germination percentage.
- The findings revealed specific SNPs that enhance or reduce phenotypic values in okra under different salt stresses, providing useful genetic markers and candidate genes for breeding more resilient okra varieties.
Article Synopsis
- Jute (Corchorus sp.) is a key fiber crop, yet the processes of its domestication and improvement are still not well understood.
- A comprehensive study using various genomic techniques revealed that dark jute (Corchorus olitorius) experienced early domestication and a moderate genetic bottleneck during breeding, highlighting the impact of soil salinity on its environmental adaptation.
- The research identified important genetic loci linked to agronomic traits and suggested potential genes like COS07g_00652 that could enhance fiber quality, offering valuable insights for future jute breeding endeavors.
Unlabelled: Rice () is a saline-alkali-sensitive crop. Saline-alkali environments can seriously affect the growth, development, and yield of rice. The mechanisms of salt tolerance and alkali tolerance in rice are different; thus, it is very important to study and explore the alkali-tolerant gene loci to improve the saline-alkali tolerance of rice varieties.
View Article and Find Full Text PDFBackground: Jute (Corchorus spp.), belonging to the Malvaceae family, is an important natural fiber crop, second only to cotton, and a multipurpose economic crop. Corchorus capsularis L.
View Article and Find Full Text PDFBackground: Jute (Corchorus spp.) is the most important natural fiber crop after cotton in terms of cultivation area and production. Salt stress greatly restricts plant development and growth.
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- Flax seeds are high in oil and unsaturated fatty acids, making them beneficial for preventing chronic diseases, especially cardiovascular issues; the focus on their oil content highlights the importance of understanding fatty acid metabolism in breeding efforts.
- A study was conducted using a natural population of 224 flax seed samples across three environments, employing genome-wide association analysis (GWAS) and RNA sequencing (RNA-seq) to identify genes linked to seed fatty acid content.
- The research uncovered 16 significant SNP loci and over 11,000 differentially expressed genes, ultimately identifying 10 candidate genes linked to fatty acid metabolism, with six showing a strong correlation with oil content in seeds of the high oil variety.
Ovate Family Protein1 (OFP1) is a regulator, and it is suspected to be involved in plant growth and development. Meanwhile, Arabidopsis Thaliana Homeobox (ATH1), a BEL1-like homeodomain (HD) transcription factor, is known to be involved in regulating stem growth, flowering time and flower basal boundary development in . Previous large-scale yeast two-hybrid studies suggest that ATH1 possibly interact with OFP1, but this interaction is yet unverified.
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- Flax (Linum usitatissimum) is categorized into oil flax, fiber flax, and oil-fiber dual purpose, playing a significant role in the food and textile industries, making genetic evaluation essential for breeding improvements.* -
- The study sequenced 224 flax varieties using SLAF-seq, resulting in over 346,000 SLAF tags and nearly 585,000 SNPs, revealing high genetic diversity in oil flax compared to the other types.* -
- This research is the first of its kind to identify multiple genetic loci associated with key agronomic traits in flax through Genome-Wide Association Studies (GWAS), contributing valuable insights for future breeding efforts.*
Background: Cold stress can cause serious abiotic damage that limits the growth, development and yield of rice. Cold tolerance during the booting stage of rice is a key factor that can guarantee a high and stable yield under cold stress. The cold tolerance of rice is controlled by quantitative trait loci (QTLs).
View Article and Find Full Text PDFJute (Corchorus spp.) is one of the most commercially important bast fiber crops in the world. However, molecular markers and high-density genetic maps are still lacking on jute compared with other crops.
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- Flax is a valuable cash crop, but there is limited knowledge about its genetic traits that impact yield and quality, prompting the need for more research.
- A study was conducted on 224 flax specimens to investigate key agronomic traits (like plant height and number of fruits) using specific techniques, including genome-wide association studies (GWAS).
- The researchers identified 42 significant SNP loci correlated with these traits and narrowed it down to 15 candidate genes that could aid in the genetic improvement of flax's agronomic characteristics.
Linolenic acid (LN) in soybean (Glycine max L. Merr.) seed mainly contributes to the undesirable odors and flavors commonly associated with poor oil quality.
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