Head pose-assisted localization of facial landmarks for enhanced fast registration in skull base surgery.

In skull base surgery, the method of using a probe to draw or 3D scanners to acquire intraoperative facial point clouds for spatial registration presents several issues. Manual manipulation results in inefficiency and poor consistency. Traditional registration algorithms based on point clouds are highly dependent on the initial pose.

Long non-coding RNA NEAT1 promotes multiple myeloma malignant transformation via targeting miR-485-5p/ABCB8.

Multiple myeloma (MM) is the second most common hematological cancer all over the world. Long non-coding RNA (lncRNA) nuclear-enriched autosomal transcript-1 (NEAT1) have been reported to play important roles in the development and progression of multiple human malignancies like MM. However, the functional role and molecular mechanism of NEAT1 in MM progression still needs more support to identify potential targets of MM.

Preoperative Prediction of Metastatic Lymph Nodes Posterior to the Right Recurrent Laryngeal Nerve in cN0 Papillary Thyroid Carcinoma.

Background: The advantages of the dissecting the metastatic lymph nodes posterior to the right recurrent laryngeal nerve (LN-prRLN) remain a great deal of controversies in papillary thyroid carcinoma (PTC) patients without clinical evidence. The purpose of our retrospective research was to investigate the predictive factors of the LN-prRLN in cN0 PTC patients.

Methods And Materials: Altogether 251 consecutive cN0 PTC participants accepted unilateral or bilateral thyroidectomy accompanied with LN-prRLN dissection between June 2020 and May 2023 were included in the research.

A Novel Molten Salt Mediated Synthesis of Mesoporous Metal Oxides with High Crystallization.

The controlled synthesis of mesoporous metal oxides remains a great challenge because the uncontrolled assembly process and high-temperature crystallization can easily destroy the mesostructure. Herein, we develop a facile, versatile, low-cost, and controllable molten salt assisted assembly strategy to synthesize mesoporous metal oxides (e.g.

Simultaneously Geometrical and Electronic Modulation of L-PtZn by Trace Ge Boosts High-performance Oxygen Reduction Reaction.

Developing a highly active, durable, and low-platinum-based electrocatalyst for the cathodic oxygen reduction reaction (ORR) is for breaking the bottleneck of large-scale applications of proton exchange membrane fuel cells (PEMFCs). Herein, ultrafine PtZn intermetallic nanoparticles with low Pt-loading and trace germanium (Ge) involvement confined in the nitrogen-doped porous carbon (Ge-L-PtZn@N-C) are reported. The Ge-L-PtZn@N-C exhibit superior ORR activity with a mass activity of 3.

Phase Engineering of Intermetallic PtBi Nanoplates for Formic Acid Electrochemical Oxidation.

Phase engineering of Pt-based intermetallic catalysts has been demonstrated as a promising strategy to optimize catalytic properties for a direct formic acid fuel cell. Pt-Bi intermetallic catalysts are attracting increasing interest due to their high catalytic activity, especially for inhibiting CO poisoning. However, the phase transformation and synthesis of intermetallic compounds usually occurring at high temperatures leads to a lack of control of the size and composition.

Coordinating Interface Polymerization with Micelle Mediated Assembly Towards Two-Dimensional Mesoporous Carbon/CoNi for Advanced Lithium-Sulfur Battery.

Lithium-sulfur battery has attracted significant attention by virtues of their high theoretical energy density, natural abundance, and environmental friendliness. However, the notorious shuttle effect of polysulfides intermediates severely hinders its practical application. Herein, a novel 2D mesoporous N-doped carbon nanosheet with confined bimetallic CoNi nanoparticles sandwiched graphene (mNC-CoNi@rGO) is successfully fabricated through a coordinating interface polymerization and micelle mediated co-assembly strategy.

Metabolic syndrome and metastatic prostate cancer correlation study, a real-world study in a prostate cancer clinical research center, Xinjiang, China.

Objective: The aim of this study was to investigate the relevance of metabolic syndrome (MetS) and metabolic scores to the occurrence, progression and prognosis of metastatic prostate cancer (mPCA), assessing the definition of the variables of metabolic syndrome, and the potential mechanisms of MetS and mPCA.

Methods: Data were obtained from the database of prostate cancer follow-up at the Urology Centre of the First Affiliated Hospital of Xinjiang Medical University (N=1303). After screening by inclusion and exclusion criteria, clinical data of 190 patients diagnosed with mPCA by pathology and imaging from January 2010 to August 2021 were finally included, including 111 cases in the MetS group and 79 cases in the Non-MetS group.

Study on a Bayes evaluation of the working ability of petroleum workers in the Karamay region, Xinjiang, China.

Objectives: Use Bayes statistical methods to analyze the factors related to the working ability of petroleum workers in China and establish a predictive model for prediction so as to provide a reference for improving the working ability of petroleum workers.

Materials And Methods: The data come from the health questionnaire database of petroleum workers in the Karamay region, Xinjiang, China. The database contains the results of a health questionnaire survey conducted with 4,259 petroleum workers.

Multifunctional Yolk-Shell Structured Magnetic Mesoporous Polydopamine/Carbon Microspheres for Photothermal Therapy and Heterogenous Catalysis.

Yolk-shell structure with magnetic core, interior void and mesoporous polymer/carbon shell demonstrate potential applications in biocatalysis, magnetic biological separation, biomedicine, and magnetic resonance imaging due to their comprehensive benefits of magnetic and mesoporous shells. Herein, yolk-shell structured magnetic mesoporous polydopamine microspheres (FeO@Void@mPDA) and the corresponding derivatives of carbon-based microspheres (FeO@Void@mCN) are successfully fabricated through an interface assembly and selective etching approach. The obtained monodisperse FeO@Void@mPDA microspheres consist of a magnetic core, a mesoporous polydopamine shell, and the large void formed between them, with perpendicular mesopores (5.

Nanoemulsion assembly toward vaterite mesoporous CaCO for high-efficient uranium extraction from seawater.

Uranium extraction from seawater is particularly significant and regarded as an indispensable strategy for satisfying the increasing demand for nuclear fuel owing to the high uranium reserves (about 4.5 billion tons) in seawater, while remains great challenges due to the low concentration, the interference of various cations and the complexity of the marine environment. Thus, developing a highly efficient adsorbent with high adsorption capacity, excellent selectivity, low cost, and facile synthesis method is significant and urgently required.

Core-Shell Nanostructured Ru@Ir-O Electrocatalysts for Superb Oxygen Evolution in Acid.

The design of highly active and durable catalysts for the sluggish anodic oxygen evolution reaction (OER) in acid remains an urgent yet challenging goal in water electrolysis. Herein, a core-shell nanostructured Ru@Ir-O catalyst with tensile strains and incorporated oxygens is introduced in the Ir shell that holds an extremely low OER overpotential of 238 mV at 10 mA cm in acid. The material also shows a remarkable 78-fold higher mass activity than the conventional IrO at 1.

Highly Dispersed Mo Sites on Pd Nanosheets Enable Selective Ethanol-to-Acetate Conversion.

The fermentation of biomass allows for the generation of major renewable ethanol biofuel that has high energy density favorable for direct alcohol fuel cells in alkaline media. However, selective conversion of ethanol to either CO or acetate remains a great challenge. Especially, the ethanol-to-acetate route usually demonstrates decentoxidation current density relative to the ethanol-to-CO route that contains strongly adsorbed poisons.

Synthesis of two new naphthalene-containing compounds and their bindings to human serum albumin.

Two naphthalene-containing compounds, 4-hydroxy-6,7-dimethoxy-1-(4-(trifluoromethyl)phenyl)-2-naphthoic acid (A) and 4-hydroxy-6,7-dimethoxy-1-phenyl-2-naphthoic acid (B), were prepared by several steps. Their bindings to human serum albumin (HSA) were studied by ultraviolet-visible (UV-vis) absorption, fluorescence, synchronous fluorescence, three-dimensional fluorescence, circular dichroism (CD) spectroscopies and molecular docking. The crystal data of these compounds show the structure of the compounds.

Three new coordination polymers based on bis(4-(4-1,2,4-triazol-4-yl)phenyl)methane: syntheses, structures, multiresponsive luminescent sensitive detection for antibiotics and pesticides, and antitumor activities.

Three novel coordination polymers (CPs), namely, {[Ag(L)(MoO)·(CHCN)]} (1), {[Zn(L)(1,4-bdc)·2(1,4-Hbdc)]} (2), {[Cd(L)(1,4-bdc)]} (3) have been synthesized under solvothermal conditions by the reaction of bis(4-(4-1,2,4-triazol-4-yl)phenyl)methane (L) and varied metal salts. Their structures are determined by single X-ray crystal diffraction, and further characterized by elemental analysis, IR, TGA and PXRD. CP 1 with ammonium molybdate as a secondary ligand displays a 2D network with (2,3,3,3,4)-connected net topology and the point symbol of {4·8}{4·8·10}{8}, CP 2 and CP 3 with 1,4-Hbdc as a secondary ligand demonstrate 3D structures with different topologies.

[Correlation of EBV Infection with Expression of TNF-α-Inducing Protein 3 Gene and A20 Protein in Hodgkin's Lmphoma].

Objective: To analyze the correlation of EBV infection with expression of TNF-α-inducing protein 3 gene and A20 protein in Hodgkin lmphoma.

Methods: The clinical data and pathological specimens of 65 cases of Hodgkin's lymphoma in our hospital were analyzed retrospectively, and the tissue chips were made for the rich area of the tumor cells. The latent membrane protein 1 encoded by EBV was measured by immunohistochemical staining, and the RNA encoded by EBV was measured by in situ hybridization to analyze the infection state.

Inhibition of HOXB7 suppresses p27-mediated acute lymphoblastic leukemia by regulating basic fibroblast growth factor and ERK1/2.

Aims: Acute lymphoblastic leukemia (ALL) is characterized by abnormal proliferation of immature lymphocytes in the bone marrow, peripheral blood, and other tissues. HOXB7 is upregulated in tumors and is related to cell proliferation and cell cycle. However, the role of HOXB7 in ALL progression remains unclear.

[Clinical Study of Patients with Myelodysplastic Syndrome Transformed into Acute Myeloid Leukemia].

Objective: To study the biological characteristics and treatment response of patients with myelodysplastic syndrome (MDS) transformed into acute leukemia(AL).

Methods: Using WHO standard method, the clinical characteristics of patients with MDS into AML were retrospectively analyzed, the related factors influencing the MDS into AML and the treatment response of patients were analyzed.

Results: Twenty-six cases (17%) of MDS were transformed into AL among 153 cases of middle and high risk MDS, all of which were AML.

[Application of narrow band imaging in early diagnosis of pharyngolaryngeal tumors].

Objective: To investigate the application value of narrow band imaging (NBI) in early diagnosis of pharyngolaryngeal tumors.

Method: A total of 106 patients received NBI endoscopy in the endoscopic diagnosis. Lesions found under the white-light endoscopy mode and NBI endoscopy mode were compared in the morphology of capillaries on lesiorn surface and the clarity of lesion rim.

Recent Design Development in Molecular Imaging for Breast Cancer Detection Using Nanometer CMOS Based Sensors.

As one of the key clinical imaging methods, the computed X-ray tomography can be further improved using new nanometer CMOS sensors. This will enhance the current technique's ability in terms of cancer detection size, position, and detection accuracy on the anatomical structures. The current paper reviewed designs of SOI-based CMOS sensors and their architectural design in mammography systems.

3-Benzyl-sulfanyl-1H-1,2,4-triazol-5-amine.

In the title mol-ecule, C(9)H(10)N(4)S, the dihedral angle between the benzene and triazole rings is 81.05 (5)°. In the crystal, N-H⋯N hydrogen bonds link the mol-ecules into infinite zigzag chains along [010].

2-(4-Chloro-phen-yl)acetamide.

In the title compound, C(8)H(8)ClNO, the acetamide group is twisted out the benzene plane with a dihedral angle of 83.08 (1)°. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds, forming layers parallel to the ab plane.

5-(4-Chloro-benz-yl)-1H-tetra-zole.

In the title compound, C(8)H(7)ClN(4), the phenyl and tetra-zole rings are inclined at a dihedral angle of 67.52 (6)°. In the crystal, mol-ecules are linked by an N-H⋯N hydrogen bond into a chain structure along [010].

Determination of glyphosate in foodstuff by one novel chemiluminescence-molecular imprinting sensor.

A novel chemiluminescence (CL) sensor for the determination of glyphosate (GLY) was made up based on molecularly imprinted polymer (MIP). The molecularly imprinted microspheres (MIMs) with a small dimension which possess extremely high surface-to-volume ratio were synthesized using precipitation polymerization with GLY as template. And then the MIMs were modified on glass sheets, which were placed at the bottom of wells of microplate as the recognizer.

Copper-catalyzed N-arylation of amides using (S)-N-methylpyrrolidine-2-carboxylate as the ligand.

(S)-N-methylpyrrolidine-2-carboxylate, a derivative of natural L-proline, was found to be an efficient ligand for the copper-catalyzed Goldberg-type N-arylation of amides with aryl halides under mild conditions. A variety of N-arylamides were synthesized in good to high yields.