Causal role of immune cells in obstructive sleep apnea hypopnea syndrome: Mendelian randomization study.

Background: Despite being one of the most prevalent sleep disorders, obstructive sleep apnea hypoventilation syndrome (OSAHS) has limited information on its immunologic foundation. The immunological underpinnings of certain major psychiatric diseases have been uncovered in recent years thanks to the extensive use of genome-wide association studies (GWAS) and genotyping techniques using high-density genetic markers (, SNP or CNVs). But this tactic hasn't yet been applied to OSAHS.

Proteomics and metabolomics of raw rhubarb and wine-processed rhubarb in the treatment of rats with intracerebral hemorrhage.

Background: To explore the mechanisms of raw rhubarb and wine-processed rhubarb treatment in a rat model of intracerebral hemorrhage (ICH).

Methods: After adapting to their environment, 30 male Wistar rats were divided into 5 treatment groups: blank control group (CK) (normal saline), sham operation group (SICH) (normal saline), ICH model group (ICH) (normal saline), ICH + raw rhubarb enema group (RO) (raw rhubarb 3.60 g/kg), and ICH + wine-processed rhubarb enema group (WRO) (wine-processed rhubarb 3.

Influencing pathways of soil microbial attributes on accumulation of heavy metals in brassica (Brassica campestris L. ssp.chinensis var.utilis Tsen et Lee) leaves.

Microbial attributes have a great impact on soil heavy metal bioavailability, yet their influencing pathway on heavy metal accumulation in crop plants remains elusive. This study was aimed to analyze the influencing pathways of microbial attributes, including microbial biomass C and N (MBC and MBN), basal soil respiration (BSR) along with the activities of catalase, urease, and sucrase, on heavy metals (i.e.

Species choice in mangrove reforestation may influence the quantity and quality of long-term carbon sequestration and storage.

Despite carbon sequestration being an important service of mangrove ecosystems, many mangrove reforestation projects have little consideration of the carbon sequestration capacity of species to be planted. Species selection is mostly based on growth rate and convenience in planting. In this study, to compare the quantity and quality of carbon stored in soil, four habitats were selected in Haijiang River Estuary, southern China to assess the contribution by different mangrove species to sediment carbon pool.

Down-regulated miR-374c and Hsp70 promote Th17 cell differentiation by inducing Fas expression in experimental autoimmune encephalomyelitis.

Objective: Fas is a positive regulator of Th17 cells differentiation in experimental autoimmune encephalomyelitis (EAE). However, its upstream regulators are still not fully determined. This study was designed to explore the upstream regulators of Fas in regulating Th17 cells differentiation in EAE.

Distribution and availability of heavy metals in soils near electroplating factories.

Comprehensive understanding of the influence of soil properties on the potential availability of heavy metals could facilitate soil environment management. This study investigated the distribution of heavy metals and their potential availability in paddy and vegetable fields around electroplating factory outlets and irrigated with its wastewater. The potential availability was assessed using secondary phase fraction (SPF) of heavy metals, including acid-soluble, reducible, and oxidizable fractions resulting from BCR sequential extraction procedure.

Association between CYP3A4 gene rs4646437 polymorphism and the risk of hypertension in Chinese population: a case-control study.

Using a case-control design, we assessed the association between single nucleotide polymorphisms of gene rs4646437 polymorphism and the risk of hypertension in Chinese population. We recruited 450 hypertension patients from The First Clinical College, Henan University of Chinese Medicine between June 2017 and May 2018. There was a significant difference in genotype distribution between case group and control group ( =18.

Interaction between GDF5 gene polymorphisms and environment factors increased the risk of knee osteoarthritis: a case-control study.

Using a case-control design, we assessed the association between single nucleotide polymorphisms (SNPs) of growth and differentiation factor 5 (GDF5)/rs143383 gene and interaction with environments and knee osteoarthritis (KOA). We recruited 288 KOA patients from the First Clinical College, Henan University of Chinese Medicine between June 2017 and May 2018. There was significant difference in genotype distribution between case group and control group (χ = 22.

Ecosystem carbon storage in forest fragments of differing patch size.

Forest fragmentation threatens the ecosystem carbon (C) storage. The distribution patterns of ecosystem C density are poorly documented for fragmented forests of differing patch size. The objectives of this study were to examine C density in these forest ecosystems and the influence of edge effects on C density.

The influence of bioavailable heavy metals and microbial parameters of soil on the metal accumulation in rice grain.

A field-based study was undertaken to analyze the effects of soil bioavailable heavy metals determined by a sequential extraction procedure, and soil microbial parameters on the heavy metal accumulation in rice grain. The results showed that Cd, Cr, Cu, Ni, Pb and Zn concentrations in rice grain decreases by 65.9%, 78.

A TiO nanotube network electron transport layer for high efficiency perovskite solar cells.

The electron transport layer (ETL) plays a critical role in high efficiency perovskite solar cells. In this study, an anodic TiO nanotube film was transformed into a TiO nanotube network film, which maintained its advantage as an efficient ETL for perovskite solar cells. Compared with the mesoporous TiO nanoparticle ETL, the TiO nanotube network ETL can increase the efficiency of perovskite solar cells by 26.

The respective effects of soil heavy metal fractions by sequential extraction procedure and soil properties on the accumulation of heavy metals in rice grains and brassicas.

This study was carried out to examine heavy metal accumulation in rice grains and brassicas and to identify the different controls, such as soil properties and soil heavy metal fractions obtained by the Community Bureau of Reference (BCR) sequential extraction, in their accumulation. In Guangdong Province, South China, rice grain and brassica samples, along with their rhizospheric soil, were collected from fields on the basis of distance downstream from electroplating factories, whose wastewater was used for irrigation. The results showed that long-term irrigation using the electroplating effluent has not only enriched the rhizospheric soil with Cd, Cr, Cu, and Zn but has also increased their mobility and bioavailability.

A Multicenter Clinical Study on Treating Post-Dural Puncture Headache with an Intravenous Injection of Aminophylline.

Background: Post-dural puncture headache (PDPH) is the most common complication of lumbar puncture. Aminophylline has been reported to be effective in the prevention of PDPH in some clinical studies, but its efficacy for the treatment of PDPH has been unproven.

Objective: To evaluate the efficacy and safety of an intravenous (IV) injection of aminophylline on PDPH.

Forest dynamics and its driving forces of sub-tropical forest in South China.

Tree mortality and recruitment are key factors influencing forest dynamics, but the driving mechanisms of these processes remain unclear. To better understand these driving mechanisms, we studied forest dynamics over a 5-year period in a 20-ha sub-tropical forest in the Dinghushan Nature Reserve, South China. The goal was to identify determinants of tree mortality/recruitment at the local scale using neighborhood analyses on some locally dominant tree species.