Curcumin ameliorates monosodium urate-induced gouty arthritis through Nod-like receptor 3 inflammasome mediation via inhibiting nuclear factor-kappa B signaling.

Background: Monosodium urate (MSU) crystals-induced inflammation is a key initiator in gouty arthritis. Curcumin is an active ingredient possessing anti-inflammatory efficacy. But the underlying mechanism is not fully understood and its effect on gouty arthritis remains elusive.

Experimental and clinical analysis of a posterolateral lumbar appendicular bone graft fusion.

Objective: This study aimed to investigate the animal experimental and clinical results of the bone graft fusion of a posterolateral lumbar appendicular bone.

Methods: 1. Sixty rabbits were randomly divided into experimental and control groups.

Biomechanics analysis for the treatment of ischemic necrosis of the femoral head by using an interior supporting system.

Objective: This work aims to perform a biomechanical test to evaluate the effect of interior supporting system and tantalum rod in simulating the treatment of ischemic necrosis of the femoral head.

Method: Three models were established: control group (group A), interior supporting system group (group B), and tantalum rod group (group C). Step-by-step loading was applied on the top of the femoral head until femoral head damage occurs by using the testing machine of the material test system.

Development of Femoral Head Interior Supporting Device and 3D Finite Element Analysis of its Application in the Treatment of Femoral Head Avascular Necrosis.

Background: The aim of this study was to develop and perform the 3D finite element analysis of a femoral head interior supporting device (FHISD).

Material And Methods: The 3D finite element model was developed to analyze the surface load of femoral head and analyze the stress and strain of the femoral neck, using the normal femoral neck, decompressed bone graft, and FHISD-implanted bone graft models.

Results: The stress in the normal model concentrated around the femoral calcar, with displacement of 0.