Publications by authors named "Dongmin R Son"
Article Synopsis
- The tree shrew (Tupaia belangeri) is being studied for its similarities to primates, particularly to understand DNA methylation and X chromosome inactivation (XCI) in their brains, using novel genome-wide methylation and transcriptomic data from their prefrontal cortex.
- The study found that female tree shrews exhibit global hypomethylation of the X chromosome compared to males, but this hypomethylation does not directly cause X chromosome gene silencing or sex-specific gene expression, although it affects the Xist gene's regulation.
- Overall, the research provides new insights into DNA methylation patterns in tree shrews and suggests that genomic CpG content may influence sex-differential
Article Synopsis
- The study presents detailed genomes of six ape species, achieving high accuracy and complete sequencing of all their chromosomes.
- It addresses complex genomic regions, leading to enhanced understanding of evolutionary relationships among these species.
- The findings will serve as a crucial resource for future research on human evolution and our closest ape relatives.
