Examining the relationship between weekend catch-up sleep and phenotypic age acceleration: Insights from a cross-sectional study.

Background: Phenotypic age acceleration (PhenoAgeAccel) is a potential aging biomarker. While weekend catch-up sleep (WCS) is commonly practiced to compensate for weekday sleep deficits, its relationship with PhenoAgeAccel remains unclear.

Methods: In this cross-sectional study, we analyzed data from 7,683 participants in the National Health and Nutrition Examination Survey (NHANES).

[Research progress on biomarkers of sepsis-associated acute kidney injury].

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis-associated acute kidney injury (SA-AKI) is a common organ dysfunction of sepsis, and its incidence and mortality are increasing,which brings heavy economic burden to patients and society. Early diagnosis and effective intervention can block the occurrence and progression of SA-AKI effectively, improve prognosis, and reduce medical costs.

Cost-effectiveness analysis of AI-based image quality control for perinatal ultrasound screening.

Purpose: This study aimed to compare the cost-effectiveness of AI-based approaches with manual approaches in ultrasound image quality control (QC).

Methods: Eligible ultrasonographers and pregnant volunteers were prospectively recruited from the Hunan Maternal and Child Health Hospital in May 2023. The ultrasonographers were randomly and evenly assigned to either the AI or Manual QC groups with baseline scores determined in June-July.

Factor Analysis of the Missed Diagnosis of Total Anomalous Pulmonary Venous Connection in Prenatal Echocardiography.

Aim: This study investigated the major factors contributing to the missed diagnosis of total anomalous pulmonary venous connection (TAPVC) in fetal echocardiography.

Methods: We retrospectively analyzed the prenatal ultrasonic images of 32 fetuses with missed diagnoses of TAPVC, compared them with autopsy and postnatal surgical records, and summarized the most likely reasons leading to the missed diagnoses.

Results: We studied a total of 157 fetuses with TAPVC, 32 (20.

Lithium-Rich Layered Oxide Cathode Materials Modified for Lithium-Ion Batteries by CoS of a 3D Rock Salt Structure Assisted by PVP.

The problem of rapid degradation of the operating voltage and discharge specific capacity of lithium-rich layered oxide (LRMs) cathode materials is a major constraint for their commercial application. In this paper, CoS coating with a 3D layered structure assisted by PVP is used to enhance the cycle life and rate performance of the LRMs material. The introduction of PVP has the following effects: (1) it reduces the solubility of CoS in the electrolyte solution and forms a stable CoS coating, and (2) it acts as a nitrogen-containing carbon matrix material and the heteroatomic dopant, and can provide more active sites to improve the conductivity of CoS.

Carbon-Coated Coaxial Cable-like ZnO@SiO@C for High-Performance Lithium-Ion Battery Anode Materials.

The practical applications of SiO anode material are limited by large volume changes and poor electronic conductivity. To reduce the effects of these problems, a carbon-coated coaxial cable-like ZnO@SiO@C composite material was prepared. ZnO has a certian electronic conductivity and an electrochemical activity, and the carbon layer can alleviate the volume variation of SiO, effectively improving the electronic conductivity and structural stability.

GCM and gcType in 2024: comprehensive resources for microbial strains and genomic data.

Microbial culture collections play a crucial role in the collection, maintenance, and distribution of quality-assured living microbial strains, along with their associated phenotypic and omics data. To enhance the find-able, accessible, interoperable, and re-usable (FAIR) data utilization of microbial resources, the World Data Center for Microorganisms (WDCM) has developed the Global Catalogue of Microorganisms (GCM) and the Global Catalogue of Type Strains (gcType). These platforms provide interactive interfaces for cataloging the holdings of collections, along with detailed annotations of type strain genomes and curated metadata, including ecosystems, growth conditions, and collection locations.

A comprehensive review on iron‒carbon microelectrolysis constructed wetlands: Efficiency, mechanism and prospects.

The traditional constructed wetlands (CWs) face challenges such as significant seasonal fluctuations in decontamination performance and susceptibility to clogging, with the bottlenecks in advanced wastewater treatment becoming increasingly prominent. The iron‒carbon microelectrolysis coupled with constructed wetlands (ICME‒CWs) represents a promising new type of CWs, capable of removing typical and emerging pollutants in water through various mechanisms including adsorption, precipitation, oxidation‒reduction, microelectrolysis, and plant‒microbial synergy. Therefore, this review summarizes the sources, preparation, and basic properties of the ICME substrate commonly used in ICME‒CWs in recent years.

Sowing depth stability analysis and test verification of no-tillage planter parallel 4-bar row unit.

The sowing depth stability and consistency of the no-tillage planter, particularly the high-speed operation, are poor. A reason for this is that the structure and parameter selection of no-tillage planter row unit profiling mechanism are unreasonable. The stability and consistency of sowing depth is beneficial when the upper and lower links of the parallel 4-bar profiling mechanism (PFPM) are parallel to the ground, but this principle is not satisfied on the uneven no-till soil.

Shengmai Powder regulates alveolar macrophage PPAR-γ and improves the chronic inflammatory state of chronic obstructive pulmonary disease.

This study examines the therapeutic effects of Shengmai Powder (SMP) on both in vitro and in vivo models of chronic obstructive pulmonary disease (COPD) and the underlying mechanisms. Cigarette smoke and cigarette extracts were used to create in vitro and in vivo models of COPD. ELISA was used to measure the levels of pro-inflammatory factors (IL-6, TNF-α, and IL-1β) in mouse lung tissue and alveolar macrophages.

Prevalence and associated factors of insomnia symptoms among doctors and nurses under the context of high prevalence of multiple infectious diseases: a cross-sectional study.

Introduction: Insomnia symptoms are prevalent among healthcare workers and represent a potential public health problem. However, there is currently insufficient evidence on insomnia symptoms among doctors and nurses under the context of high prevalence of multiple infectious diseases after the pandemic in China. The purpose of this study was to analyze the prevalence of insomnia symptoms among doctors and nurses in third-grade class-A general hospitals under the context of high prevalence of multiple infectious diseases, and to explore the influence of demographic characteristics, work-related factors, health and lifestyle-related factors on insomnia symptoms.

Gender differences in the relationship between the triglyceride-glucose index and serum Klotho concentrations among the middle-aged and elderly: a cross-sectional analysis.

Background: The triglyceride-glucose (TyG) index is recognized as a robust indicator for evaluating insulin resistance (IR). Despite the well-documented anti-aging biological functions of Klotho protein, its correlation with the TyG index remains unexplored.

Methods: A cross-sectional analysis was conducted involving participants from the National Health and Nutrition Examination Surveys (NHANES) 2007-2016.

[Construction and validation of a risk nomogram for sepsis-associated acute kidney injury in intensive care unit].

Objective: To construct and validate a nomogram model for predicting sepsis-associated acute kidney injury (SA-AKI) risk in intensive care unit (ICU) patients.

Methods: A retrospective cohort study was conducted. Adult sepsis patients admitted to the department of ICU of the 940th Hospital of Joint Logistic Support Force of PLA from January 2017 to December 2022 were enrolled.

COVID-19 in the Tibet, China, the roof of the world: a comparative analysis of high-altitude residents and newcomers.

Background: After a 920-day hiatus, COVID-19 resurged in the Tibet Autonomous Region of China in August 2022. This study compares the characteristics of COVID-19 between high-altitude residents and newcomers, as well as between newcomers and lowlanders.

Methods: This multi-center cohort study conducted at the Third People's Hospital of Tibet Autonomous Region and Beijing University Shenzhen Hospital, included 520 high-altitude resident patients, 53 high-altitude newcomer patients, and 265 lowlander patients infected with the Omicron variant.

Phosphoenolpyruvate carboxykinase 2-mediated metabolism promotes lung tumorigenesis by inhibiting mitochondrial-associated apoptotic cell death.

Background: It is unknown how cancer cells override apoptosis and maintain progression under nutrition-deprived conditions within the tumor microenvironment. Phosphoenolpyruvate carboxykinase (PEPCK or PCK) catalyzes the first rate-limiting reaction in gluconeogenesis, which is an essential metabolic alteration that is required for the proliferation of cancer cells under glucose-limited conditions. However, if PCK-mediated gluconeogenesis affects apoptotic cell death of non small cell lung cancer (NSCLC) and its potential mechanisms remain unknown.

High-level feature-guided attention optimized neural network for neonatal lateral ventricular dilatation prediction.

Background: Periventricular-intraventricular hemorrhage can lead to posthemorrhagic ventricular dilatation or even posthemorrhagic hydrocephalus if not detected promptly. Sequential cranial ultrasound scans are typically used for their diagnoses. Nonetheless, manual image audit has numerous disadvantages.

Barriers and facilitators to self-management among women with gestational diabetes: A systematic review using the COM-B model.

Background: Gestational diabetes mellitus is a common complication during pregnancy, and its prevalence rates have increased dramatically in recent years. Treatment of gestational diabetes requires the active self-management, however, this can be challenging. Understanding the barriers and facilitators of adherence to self-management recommendations is essential for designing effective interventions.

Mechanism of probiotics in the intervention of colorectal cancer: a review.

The human microbiome interacts with the host mainly in the intestinal lumen, where putrefactive bacteria are suggested to promote colorectal cancer (CRC). In contrast, probiotics and their isolated components and secreted substances, display anti-tumor properties due to their ability to modulate gut microbiota composition, promote apoptosis, enhance immunity, resist oxidation and alter metabolism. Probiotics help to form a solid intestinal barrier against damaging agents via altering the gut microbiota and preventing harmful microbes from colonization.

Heterologous expression and characterization of a dye-decolorizing peroxidase from Ganoderma lucidum, and its application in decolorization and detoxifization of different types of dyes.

Dye-decolorizing peroxidases (DyPs) belong to a novel superfamily of heme peroxidases that can oxidize recalcitrant compounds. In the current study, the GlDyP2 gene from Ganoderma lucidum was heterologously expressed in Escherichia coli, and the enzymatic properties of the recombinant GlDyP2 protein were investigated. The GlDyP2 protein could oxidize not only the typical peroxidase substrate ABTS but also two lignin substrates, namely guaiacol and 2,6-dimethoxy phenol (DMP).

Chrdl1-mediated BMP4 inhibition disrupts the balance between retinal neurons and Müller Glia.

Chordin-like 1 (CHRDL1) is a secreted protein that serves as an endogenous antagonist of bone morphogenetic proteins (BMPs). In the developing retina, Bmp4 has been demonstrated to be essential for sustaining the proliferation of progenitor cells and facilitating the differentiation of glial cells. Despite these efforts, the precise effects of Bmp4 inhibition on the developing retina are yet to be fully understood.