Synopsis of recent research by authors named "Dongling Ding"
- Dongling Ding's research primarily focuses on the molecular mechanisms by which genetic mutations, specifically in the SPOP gene, influence prostate cancer pathogenesis, particularly through enhancing cancer cell survival and resistance to chemotherapy.
- In a significant study published in 2019, Ding and colleagues discovered that SPOP mutations lead to the upregulation of Caprin1-dependent stress granule assembly, which is associated with increased resilience of prostate cancer cells under therapeutic stressors like docetaxel.
- Additionally, Ding has conducted exploratory studies on the diversity of actinomycetes in the roots and rhizospheric soil of the medicinal tree peony (Paeonia suffruticosa), utilizing high-throughput sequencing to identify various operational taxonomic units, which provides insights into the microbial ecology associated with medicinal plants.
