Publications by authors named "Donglei Liao"

Background: Contactin-associated protein-2(CASPR2) antibody-associated autoimmune encephalitis(AE) is rare in children. This study aimed to report the clinical characteristics and long-term outcome of CASPR2 autoimmunity in children to expand the disease spectrum.

Methods: Children who were hospitalized in our hospital with clinically suspected AE from May 2015 to April 2022 and underwent neuronal surface antibodies detections were retrospectively analyzed.

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Article Synopsis
  • The study investigates the effectiveness of the Head-up tilt test (HUTT) in diagnosing pediatric vasovagal syncope by comparing two testing methods: basic head-up tilt (BHUT) and sublingual nitroglycerine head-up tilt (SNHUT).
  • A retrospective analysis was conducted on data from 2,513 children, revealing that those in the BHUT group showed higher baseline characteristics such as age, height, weight, and various blood pressure measurements compared to the SNHUT group.
  • Findings indicate that having previous syncopal episodes increases the likelihood of a positive BHUT result, suggesting that syncope is a significant risk factor for diagnosing this condition in children.
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Objectives: To characterize the clinical and radiological features, treatment responses and outcomes of children with co-existing anti-N-methyl-D-aspartate receptor(NMDAR) and myelin oligodendrocyte glycoprotein(MOG) antibody-associated encephalitis.

Methods: Clinical manifestations, imaging features, effectiveness of treatment and outcomes of patients who were cerebral spinal fluid(CSF)-positive for NMDAR-antibody(NMDAR-ab) and seropositive for MOG-antibody(MOG-ab) were analyzed.

Results: Twelve patients including 8 females and 4 males were enrolled.

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Unlabelled: Vasovagal syncope (VVS) is a clinically common neurally mediated syncope. The relationship between different hemodynamic types of VVS and clinical syncopal symptoms has not been reported. The purpose of this research is to explore relationship between hemodynamic types and syncopal symptoms in pediatric VVS.

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Background: pneumonia (PCP) is a serious opportunistic infection in immunocompromised children. Real-time polymerase chain reaction (PCR) is widely used for the diagnosis of PCP due to its good accuracy. However, the diagnostic performance of multiplex real-time PCR on sputum in children with PCP has never been explored.

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Objective: To explore the change of the amplitude of P wave, T wave and ST segment of 12 lead electrocardiogram (ECG) in children with breath holding spell.


Methods: A total of 29 children (24 males and 5 females) with breath holding spell in Second Xiangya Hospital, Central South University were enrolled for this study from October, 2009 to September, 2015. Their ages ranged from 3 months to 6 years, with an average of 1.

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Objective: To explore the circadian rhythm of neurally mediated syncope (NMS).

Methods: 411 patients with NMS (165 males and 246 females aged from 3 to 68years) were included in the study. All subjects underwent head-up tilt test (HUTT) and were carefully asked about the number of syncopal attacks and the periods (morning 06:00am-12:00am, afternoon 12:00am-18:00pm, evening 18:00pm-24:00pm, night 00:00am-06:00am) in which episodes occurred in.

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