Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways.

Alopecia areata (AA) is an autoimmune dermatological disease with multifactorial etiology and is characterized by reversible hair loss in patches. AA may be closely related to emotional stress and influenced by psychological factors as part of its pathophysiology; however, its etiology remains predominantly unknown. This review aimed to elucidate the association between AA occurrence and the neuropeptide substance P (SP) and corticotropin-releasing hormone (CRH), which are secreted during emotional stress, and have been understood to initiate and advance the etiopathogenesis of AA.

Seeking Pleasure or Meaning? The Different Impacts of Hedonic and Eudaimonic Tourism Happiness on Tourists' Life Satisfaction.

Although hedonic tourism happiness and eudaimonic tourism happiness coexist in tourism experiences, extant research has primarily approached them and their impact on tourists' life satisfaction separately. Therefore, the purpose of this research is to investigate the impact on life satisfaction of the two types of happiness tourists experience in various activities they encounter in tourist venues and their asymmetric effects. A survey was conducted among tourists who had tourism experiences within a year (October 2018 to September 2019) either abroad or Jeju island, and 736 responses were used in the analysis.