Continuous exposure to 60 Hz extremely low frequency magnetic field at 10-14 mT promotes various human cell proliferation by activating extracellular-signal-regulated kinase.

We previously showed that 60 Hz extremely low-frequency magnetic fields (ELF-MF) at 6 mT promote various humancell proliferation. This study investigated the effects of 60 Hz ELF-MF at 10-16 mT on various mammalian cells, including human cervical carcinoma, rat neuroblastoma, liver cancer stem cells, immortalized normal hepatic cells, and normal fibroblasts. Using a revised ELF-MF-generating device that increases magnetic flux density stably without thermal effects, we exposed cells to 10 and 16 mT ELF-MF for 72 h.

Non-thermal atmospheric pressure plasma induces epigenetic modifications that activate the expression of various cytokines and growth factors in human mesoderm-derived stem cells.

Non-thermal atmospheric pressure plasma (NTAPP) has been reported to induce wound healing, activation of immune cells, and proliferation of mesoderm-derived adult stem cells in human. However, the mechanism by which NTAPP activates these physiological effects is poorly understood. Here, we examined whole genome expression profiles of adipose tissue-derived stem cells (ASCs), the proliferation of which is induced by NTAPP.