Evaluation of Aminated Nano-Silica as a Novel Shale Stabilizer to Improve Wellbore Stability.

The issue of wellbore instability poses a significant challenge in the current exploration of shale gas reservoirs. Exploring more efficient shale stabilizers has always been a common goal pursued by researchers. In this paper, a novel shale stabilizer, denoted as ANS, was prepared by employing a silane-coupling modification method to graft (3-Aminopropyl) triethoxysilane (APTES) onto the surface of nano-silica.

[Application of metronidazole combined with minocycline in reducing infection after dental implant in patients with localized periodontitis].

Purpose: To explore the value of metronidazole combined with minocycline in reducing infection after dental implant in patients with localized periodontitis.

Methods: A total of 120 patients with localized periodontitis who underwent dental implantation in the Department of Stomatological, Shanghai Pudong New Area People's Hospital from August 2021 to September 2022 were selected. According to the way of postoperative infection prevention, the patients were divided into control group and experimental group, with 60 patients in each group.

Genetic association of the epidermal growth factor gene polymorphisms with peri-implantitis risk in Chinese population.

Peri-implant disease is an inflammatory disease and is related to genetic heterogeneity. Considering the genetic association of epidermal growth factor () gene polymorphisms with the susceptibility of periodontitis, its genetic association with peri-implantitis risk in a Chinese Han population was explored. Three hundred individuals who underwent dental implants were recruited, and divided into healthy implant group and peri-implantitis group.