Publications by authors named "Dongchong Kang"
Objective: Lateralized periodic discharges (LPDs), which constitute an abnormal electroencephalographic (EEG) pattern, are most often observed in critically ill patients with acute pathological conditions, and are less frequently observed in chronic conditions such as focal epilepsies, including temporal lobe epilepsy (TLE). Here we aim to explore the pathophysiological mechanism of LPD in TLE.
Methods: We retrospectively selected 3 patients with drug-resistant TLE who simultaneously underwent EEG and electrocorticography (ECoG) and demonstrated LPDs.
We report a 58-year-old woman who suddenly developed brain infarction with weakness of the left lower extremity and left perioral dysesthesia during postoperative tamoxifen therapy for breast cancer and prednisolone therapy for rheumatoid arthritis. Diffusion-weighted images detected multiple areas of hyperintensity in the posterior circulation system of the brain. Despite extensive examinations, we could not identify any embolic sources except hypoplasia of the right vertebral artery.
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- * Imaging studies indicated an occluded branch of the left middle cerebral artery, while echocardiography confirmed the presence of a patent foramen ovale and deep vein thrombosis in the femoral veins.
- * Treatment with apixaban was effective in preventing further strokes and reducing the thrombosis, suggesting it could be a viable alternative to warfarin for patients with protein S deficiency in preventing recurrent ischemic strokes.