Critical Decision-Making Issues in Disaster Relief Supply Management: A Review.

This paper comprehensively reviews the literature related to disaster relief supply management in recent years by taking the perspectives of three critical decision-making issues, i.e., coordination issues, facility location decisions, and inventory decisions.

Magnetic Force-driven in Situ Selective Intracellular Delivery.

Intracellular delivery of functional materials holds great promise in biologic research and therapeutic applications but poses challenges to existing techniques, including the reliance on exogenous vectors and lack of selectivity. To address these problems, we propose a vector-free approach that utilizes millimeter-sized iron rods or spheres driven by magnetic forces to selectively deform targeted cells, which in turn generates transient disruption in cell membranes and enables the delivery of foreign materials into cytosols. A range of functional materials with the size from a few nanometers to hundreds of nanometers have been successfully delivered into various types of mammalian cells in situ with high efficiency and viability and minimal undesired effects.

Microfluidic platform for probing cancer cells migration property under periodic mechanical confinement.

Cancer cell migration and invasion, which are involved in tumour metastasis, are hard to predict and control. Numerous studies have demonstrated that physical cues influence cancer cell migration and affect tumour metastasis. In this study, we proposed the use of a microchannel chip equipped with a number of vertical constrictions to produce periodic compression forces on cells passing through narrow channels.