Publications by authors named "DongZhi Li"

Background: Fomesafen is a selective herbicide widely used to control post-emergent broad-leaf weeds in soybean and peanut fields. Because of its persistent nature in soil, it can suppress subsequent crops, including wheat. There is limited information focusing on methods of protecting wheat from fomesafen injury by soil residue.

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Fomesafen is a herbicide with long persistence in soil, causing damage to succeeding crops. Dichlormid is a widely used safener protecting maize from chloroacetanilide and thiocarbamate injury. We found that dichlormid treatment could restore the growth of wheat seedlings exposed to fomesafen stress.

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Variants of the ACTG2 gene cause autosomal dominant ACTG2 visceral myopathy, a disorder of smooth muscle dysfunction of the bladder and gastrointestinal system. Bladder involvement can behave as fetal megacystis (FM). We report four prenatal cases of ACTG2 visceral myopathy.

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The application of machine learning (ML) to predict reaction yields has shown remarkable accuracy when based on high-throughput computational and experimental data. However, the accuracy significantly diminishes when leveraging literature-derived data, highlighting a gap in the predictive capability of the current ML models. This study, focusing on Pd-catalyzed carbonylation reactions, reveals that even with a data set of 2512 reactions, the best-performing model reaches only an of 0.

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Objective: To determine the exome sequencing results in fetuses with bilateral renal agenesis (BRA).

Methods: This was a retrospective study of 14 cases with BRA diagnosed on second trimester anatomy ultrasound. All cases underwent invasive prenatal diagnosis.

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Objective: The aim of this study was to investigate the value of genetic testing using exome sequencing (ES) in oligohydramnios pregnancies with or without other structural abnormalities.

Materials And Methods: A total of 110 singleton pregnancies complicated by oligohydramnios were enrolled, including 52 of isolated oligohydramnios and 58 of non-isolated oligohydramnios. All fetal samples were first tested by quantitative fluorescent polymerase chain reaction (QF-PCR) and followed by chromosomal microarray analysis (CMA).

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Article Synopsis
  • - The study investigates the genetic causes of right aortic arch (RAA) in fetuses, using chromosomal microarray analysis (CMA) and whole exome sequencing (WES), emphasizing the need for genetic evaluation despite many RAA cases having good outcomes.
  • - Among 153 fetuses studied, 64.7% had isolated RAA, while 35.3% had non-isolated RAA; chromosomal abnormalities were found more frequently in non-isolated cases and those with additional heart or body issues.
  • - Key findings include clinically significant genetic variations in a small percentage of cases, with higher premature birth and termination rates for non-isolated RAA compared to isolated RAA, reinforcing the importance of
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Pesticides are extensively utilized in contemporary agriculture to manage pests, enhance crop yields, and sustain productivity. Nevertheless, the persistent herbicide represents a dual-edged weapon. On one hand, their prolonged efficacy enables reduced application frequency during crop growth seasons, resulting in cost savings on labor.

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  • This study examines the effects of 17q12 copy number variants (CNVs) in fetuses, focusing on their physical characteristics during pregnancy.
  • The analysis included 48 fetuses with 17q12 microdeletions or microduplications, revealing that 94.6% of fetuses with deletions showed significant kidney issues, while those with duplications often had duodenal obstructions and cardiac abnormalities.
  • Despite the complexity and variability of 17q12 CNVs, the research suggests that the immediate outlook for affected fetuses is generally positive.
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Objective: The recurrent 1q21.1 microdeletion syndrome is an autosomal dominant disorder and is characterized by dysmorphic facial features, microcephaly, developmental delay, and congenital defects. However, most studies on the distal deletions in the 1q21.

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Article Synopsis
  • A systematic analysis investigated the molecular causes of fetal cleft lip and/or palate (CL/P) and their link to genetic variations known as copy number variations (CNVs), focusing on how these factors affect birth outcomes.
  • In a retrospective study involving 358 pregnancies, chromosomal microarray (CMA) tests revealed clinically significant variants in 29 fetuses, with higher detection rates in cases of combined cleft palate (CP) and cleft lip with palate (CLP) compared to isolated cleft lip (CL) cases.
  • The findings highlight the effectiveness of CMA as a prenatal diagnostic tool, indicating that the presence of additional ultrasound abnormalities increases the chance of finding significant genetic anomalies in fetuses with CL/P.
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As an important pest on winter wheat, Rhopalosiphum padi (L.) causes damage to the wheat yield by sucking plant nutrients, transmitting plant viruses and producing mildew. R.

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α-thalassemia major (α-TM) often causes Hb Bart's (c4) hydrops fetalis and severe obstetric complications in the mother. Step-wise screening for couples at risk of having offspring(s) affected by α-TM is the efficient prevention method but some rare genotypes of thalassemia cannot be detected. A 32-year-old male with low HbA2 (2.

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Objective: To present the prenatal sonographic features and genomic spectrum of pregnancies with fetal Bardet-Biedl syndrome (BBS).

Methods: This was a retrospective study of 11 cases with BBS diagnosed by prenatal ultrasound and confirmed by genetic testing. Clinical and laboratory data were collected and reviewed for these cases, including maternal demographics, prenatal sonographic findings, molecular testing sequencing results, and pregnancy outcomes.

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Trio exome sequencing was performed on a female fetus with an increased nuchal translucency, along with nasal bone hypoplasia, suspected cleft palate and abnormal outflow tract of the heart. A de novo heterozygous variant c.5500_5507del, p.

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Carboxylesterases (CarEs) is an important detoxification enzyme system in phase Ⅰ participating in insecticides resistance. In our previous study, a CarEs gene from lepidoptera class, was screened out to be upregulated in a pyrethroids and organophosphates resistant population. Its overexpression was verified in two field-collected populations of (Lepidoptera: Noctuidae) resistant to pyrethroids and organophosphates by qRT-PCR.

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