To solve the problem of low chemical oxygen demand (COD)/N and poor efficiency of single-stage sequencing batch reactor (SBR) or anoxic/oxic process (A/O) in treatment of digested effluent of swine wastewater, combined SBR-A/O and A/O-SBR processes were employed in the addition ratios of 0, 10%, 30%, and 40% (V/V)) of raw swine wastewater (RS). Analysis of pollutants removal performance of SBR-A/O and A/O-SBR systems showed no significant difference between the two systems without RS addition. However, after adding RS, the pollutants removal efficiency of the two systems increased with the increase in the ratio of RS, with SBR-A/O system presenting better pollutants removal performance than A/O-SBR system.
View Article and Find Full Text PDFBackground: Acute type A aortic dissection (ATAAD) is a life-threatening condition that often requires total aortic arch replacement (TAR) combined with frozen elephant trunk (FET) implantation. Despite advancements in surgical techniques and preoperative management, postoperative acute kidney injury (AKI) remains a prevalent complication that significantly affects patient prognosis, particularly severe AKI. The aim of this study was to investigate the predictive value of perioperative lactate levels in severe postoperative AKI after TAR.
View Article and Find Full Text PDFBryostatins are a family of marine natural products that have garnered significant interests, as evidenced by over 40 clinical trials. However, their extremely low natural abundance has severely limited further research. Despite significant efforts, which have led to the total synthesis of seven bryostatin members by eight independent research groups, these complex molecules present persistent challenges for stereocontrolled, large-scale, and especially divergent synthesis.
View Article and Find Full Text PDFTongue squamous cell carcinoma (TSCC) is a prevalent malignancy that afflicts the head and neck area and presents a high incidence of metastasis and invasion. Accurate diagnosis and effective treatment are essential for enhancing the quality of life and the survival rates of TSCC patients. The current treatment modalities for TSCC frequently suffer from a lack of specificity and efficacy.
View Article and Find Full Text PDFRNA modifications are emerging as critical cancer regulators that influence tumorigenesis and progression. Key modifications, such as N6-methyladenosine (mA) and 5-methylcytosine (mC), are implicated in various cellular processes. These modifications are regulated by proteins that write, erase, and read RNA and modulate RNA stability, splicing, translation, and degradation.
View Article and Find Full Text PDFThe bi-transition-metal interstitial compounds (BTMICs) are promising for water electrolysis. The previous BTMICs are usually composed of irregular particles. Here, this work shows the synthesis of novel 1D CoMoC-based heterojunction nanowires (1D Co/CoMoC) with diameters about 50 nm and a length-to-diameter ratio about 20 for efficient water electrolysis.
View Article and Find Full Text PDFWith the development of industry, agriculture, and aquaculture, excessive ammonia nitrogen mainly involving ionic ammonia (NH) and molecular ammonia (NH) has inevitable access to the aquatic environment, posing a severe threat to water safety. Photocatalytic technology shows great advantages for ammonia nitrogen removal, such as its efficiency, reusability, low cost, and environmental friendliness. In this study, CP (g-CN/CoP) composite materials, which exhibited high-efficiency ammonia nitrogen removal, were synthesized through a simple self-assembly method.
View Article and Find Full Text PDFNonalcoholic fatty liver disease (NAFLD) is characterized by over 5% hepatic fat accumulation without secondary causes. The prevalence of NAFLD has escalated in recent years due to shifts in dietary patterns and socioeconomic status, making it the most prevalent chronic liver disease and a significant public health concern globally. Serum uric acid (SUA) serves as the end product of purine metabolism in the body and is intricately linked to metabolic syndrome.
View Article and Find Full Text PDFTriggered by the vulnerability to atherosclerotic plaques, cardiovascular diseases (CVDs) have become a main reason for high mortality worldwide. Thus, there is an urgent need to develop functional molecular imaging modalities to improve the detection rate of vulnerable plaques. In this study, polyethyleneimine (PEI) was coated on the surface of mesoporous silica nanoprobes (MSN) loaded with GdO (MSN@GdO), followed by coupling the fluorescent dye carboxylated heptamethine cyanine (IR808), and then the dextran sulfate (DS) was modified on the surface of MSN@GdO@IR808 by electrostatic adsorption, to construct a targeted and pH-responsive magnetic resonance (MR)/near-infrared fluorescence imaging (NIRF) dual-modal nanoprobe (MSN@GdO@IR808@DS nanoparticles).
View Article and Find Full Text PDFNeutrophils, the most abundant type of granulocyte, are widely recognized as one of the pivotal contributors to the acute inflammatory response. Initially, neutrophils were considered the mobile infantry of the innate immune system, tasked with the immediate response to invading pathogens. However, recent studies have demonstrated that neutrophils are versatile cells, capable of regulating various biological processes and impacting both human health and disease.
View Article and Find Full Text PDFThis work of fiction depicts a scenario in which a faculty member felt they were criticized unfairly and inappropriately for honesty on a faculty survey, which reflected poorly on administration. The faculty member was left struggling with how to respond to conflicting feelings and perception of misaligned goals and mission. Simultaneously, the department chair felt they were blindsided by issues that could have been addressed without the embarrassment of a poor survey.
View Article and Find Full Text PDFIn this paper, a wideband optically transparent absorber based on multilayer indium tin oxide (ITO) films is designed, fabricated, and measured. The structure uses polyethylene terephthalate (PET) and ITO films to replace the dielectric substrate and metal pattern of the traditional absorber to achieve optical transparency characteristics. The absorption of the proposed absorber is above 90% from 4.
View Article and Find Full Text PDFThe low plating/stripping efficiency of zinc anodes, dendrite growth, and high freezing points of aqueous solutions hinder the practical application of aqueous zinc-ion batteries. This paper proposes a zwitterionic permeable network solid-state electrolyte based on the "anchor-capture" effect to address these problems by incorporating proline (Pro, a biological antifreeze agent) into the electrolyte. Extensive validation tests, Quantum Chemistry (QC) calculations, Molecular Dynamics (MD) Simulations, and ab initio molecular dynamics simulations consistently indicate that the amino groups in proline adsorb onto the Zn metal surface, stabilizing the zinc anode-electrolyte interface, suppressing side reactions from water decomposition, and homogenizing zinc-ion flux.
View Article and Find Full Text PDFJ Assist Reprod Genet
December 2024
The design of polyelectrolyte hydrogel with unique tensile and adhesive properties which can be applied across disciplines has gradually become a popular trend. However, the phenomenon of global warming and the emergence of extreme weather, it still faces some urgent problems that should be solved, such as the optimal utilization of polyelectrolyte hydrogel across a wide range of temperatures. Herein, a wide temperature sensitivity and conductivity hydrogel based on sodium alginate, acrylamide and N-isopropylacrylamide was constructed, which exhibited excellent adhesion and temperature conductivity.
View Article and Find Full Text PDFA ligand-controlled regiodivergent and enantioselective ring expansion of benzosilacyclobutenes with internal naphthyl alkynes has been achieved by adjusting the ligand cavity size. The ligand ()-8-binaphthyl phosphoramidite, featuring small methyl groups on its arms, provides a spacious cavity that favors sterically demanding Si-Csp ring expansion, predominantly yielding axially chiral ()-1-silacyclohexenyl arenes. In contrast, the ligand ()-spiro phosphoramidite, with bulky -Bu groups on its arms, offers a compact cavity that facilitates less sterically demanding Si-Csp ring expansion, leading primarily to axially chiral ()-2-silacyclohexenyl arenes.
View Article and Find Full Text PDFCO hydrogenation to hydrocarbons under high space velocity is crucial for industrial applications, but traditional Fe-based catalysts often suffer from the low activity and poor stability. Herein, we report a new tandem catalyst system combining Pt/TiO catalysts with FeC catalysts for the direct conversion of CO into C-C hydrocarbons under high space velocity. The Pt/TiO component promotes *CO intermediate production with an enhanced Reverse Water-Gas Shift (RWGS) reaction efficiency, providing a highly reactive species for the FeC catalyst to achieve Fischer-Tropsch synthesis (FTS).
View Article and Find Full Text PDFA large amount of greenhouse gas nitrous oxide (NO) will be produced during the biological nitrogen removal process for organic wastewater of low C/N ratio. One of the effective methods to solve this problem is to incorporate inexpensive carbon source. In this study, raw wastewater (RW) from pig farm, that was not anaerobically digested, was utilized as exogenous carbon in both A/O and SBR aerobic reactor to treat liquid digestate with high ammonia nitrogen and low C/N ratio.
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