3D-printed TiC/polycaprolactone composite scaffold with a DOPA-SDF1 surface modified for bone repair.

Large bone defects are a major clinical challenge in bone reconstructive surgery. 3D printing is a powerful technology that enables the manufacture of custom tissue-engineered scaffolds for bone regeneration. Electrical stimulation (ES) is a treatment method for external bone defects that compensates for damaged internal electrical signals and stimulates cell proliferation and differentiation.

[Long-term outcomes of Chiari osteotomy for Legg-Calvé-Perthes disease in children].

Objective: To explore long-term outcomes of Chiari osteotomy for Legg-Calvé-Perthes disease in children with type Catterall III or IV, and to analyze clinical effect of osteotomy angle on clinical and radiographic results.

Methods: From March 2005 to July 2013, 26 children with Legg-Calvé-Perthes disease with type Catterall III or IV were treated by Chiari osteotomy, including 17 males and 9 females, aged from 4 to 13 years old with an average of (8.9±2.

[Phase I total hip replacement for severe hip osteoarthritis with proximal femoral fractures].

Objective: To investigate the effect and prognosis of stage I total hip replacement in the treatment of severe hip osteoarthritis with proximal femoral fracture.

Methods: From July 2014 to October 2017, 8 patients with severe end-stage hip disease and proximal femoral fracture were treated with stage I total hip replacement including 6 males and 2 females, aged 59 to 72 years old with an average age of 65 years old, involving 4 femoral head necrosis with proximal femoral fracture in the right side, 3 femoral head necrosis with proximal femoral fracture in the left side, and 1 left acetabular dysplasia with proximal femoral fracture in the left side. The average time from injury to operation was 7 days.

[Repairing diabetic rats with bone defect by VEGF165 gene modified adipose-derived stem cells].

Objective: To explore repairing results of VEGF165 gene modified adipose-derived stem cells for diabetic rats with bone defect.

Methods: Seventy-eight male Wistar rats weighted 180 to 220 g were selected, 72 rats were established diabetic animal models by streptozotocin inducement method, blood glucose level was more than 16.7 mmol/L.

TAZ overexpression is associated with epithelial-mesenchymal transition in cisplatin-resistant gastric cancer cells.

Gastric cancer is one of the common malignant diseases. The poor treatment outcome is mainly due to chemotherapeutic resistance. Therefore, it is important to determine the molecular mechanism of drug resistance in gastric cancer.

[Clinical and radiographic evaluation for total hip arthroplasty in treatment of bony ankylosis of hips].

Objective: To evaluate the clinical and radiographic effects of total hip arthroplasty (THA) in the treatment of bony ankylosis of hips.

Methods: From January 2003 to August 2009, 20 patients (30 hips) with bony ankylosis of hips were treated with THA. There were 12 males and 8 females, with an average age of 36 years old.

[Treatment of humeral supracondylar fracture in children with neurovascular complications].

Objective: To discuss the treatment methods of humeral supracondylar fracture in children with neurovascular complications.

Methods: Ninety-six children (59 males, 37 females) with humeral supracondylar fractures were treated by surgery from February 2002 to November 2007, with the mean age of 6.4 years old (ranged from 4 to 16 years).