Publications by authors named "Dong-na Fu"
[Suppressing the growth of Hep-2 human laryngeal cancer cells by silencing survivin gene in vitro and in vivo].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
August 2010
Article Synopsis
- The study aimed to investigate how silencing the protein survivin affects the growth of Hep-2 human laryngeal cancer cells both in the lab (in vitro) and in living organisms (in vivo).
- Researchers used a specific siRNA to reduce survivin levels, leading to a significant decrease in cell proliferation and a reduction in tumor size in mice.
- The results showed that survivin silencing resulted in decreased tumor growth and increased cancer cell death, indicating its potential as a therapeutic target for laryngeal cancer.