Publications by authors named "Dong-fu Chen"
Objectives: To investigate the relationship between systemic inflammatory response and short-term mortality in patients with non-cirrhotic chronic severe hepatitis (CSH) by using several indicators of inflammation including neutrophil-to-lymphocyte ratio (NLR), neutrophil (NEU), white blood cell (WBC), platelet-to lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR).
Methods: Data were collected from two prospectively enrolled CATCH-LIFE noncirrhotic cohorts. Cox regression analysis was used to investigate the association between systemic inflammatory biomarkers and 90-day liver transplant (LT)-free mortality.
Performance of thoracic radiotherapy may be assisted by the use of thoracoabdominal flat immobilization devices (TAFIDs) and integrated cervicothoracic immobilization devices (ICTIDs). This study was performed to compare setup errors of TAFIDs and ICTIDs. Forty-four patients with lung cancer were retrospectively reviewed; 22 patients were immobilized with a TAFID and 22 with an ICTID.
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- Portal vein thrombosis (PVT) is a serious issue in cirrhosis patients and is more common in those experiencing acute decompensation (AD), with a prevalence of 9.36% compared to 5.24% in those without AD.
- Recent PVT was found in 63.37% of patients with cirrhosis and AD, and these patients also had higher rates of variceal bleeding and elevated D-dimer levels.
- Despite the higher incidence of bleeding and complications, the one-year mortality rate was similar between patients with and without PVT, highlighting the need for preventive measures and regular screenings in vulnerable cirrhosis patients.
Background: The role of thoracic radiation therapy (TRT) after chemotherapy (CHT) in extensive-stage small cell lung cancer (ES-SCLC) has not been well defined. We investigated whether intensity-modulated radiotherapy (IMRT) improves outcomes in ES-SCLC after CHT compared to CHT alone.
Methods: A total of 292 patients who reached a complete response (CR), partial response (PR), or stable disease (SD) after CHT were assigned into groups: CHT + TRT and CHT alone.
Article Synopsis
- Thymomas often recur after complete surgical removal, and this study investigated the patterns and predictors of such relapses in 331 patients over a median follow-up of 59 months.
- The recurrence rate was found to be 6.9%, with most relapses occurring locally in the pleura and tumor bed, and factors like initial Masaoka stage, tumor size, and histological type being significant predictors of recurrence.
- The findings suggest that regional recurrence is the most common pattern, and larger tumor size, advanced stage, and specific tumor types, especially type B3, are associated with a higher risk of relapse.
Objective: To compare the treatment results of three-dimensional conformal radiotherapy (3D-CRT) and conventional radiotherapy (2D) for patients with locally advanced non-small-cell lung cancer (NSCLC).
Methods: Five hundred and twenty seven patients with stage III NSCLC treated between Jan 2000 and Dec 2006 were included in this study. Among them, 253 cases were treated with 3D-CRT, and 274 with conventional radiotherapy.
[Thoracic radiation therapy improves the prognosis for patients with extensive stage small-cell lung cancer].
Zhonghua Zhong Liu Za Zhi
February 2011
Objective: To evaluate the effect of thoracic radiation therapy (TRT) on patients with extensive stage small-cell lung cancer (SCLC).
Methods: One hundred and fifty-four patients with extensive stage SCLC treated in our department between January 2003 and December 2006 were enrolled in this study. Eighty nine patients received chemotherapy and thoracic radiation therapy (ChT/TRT), and 65 patients were treated with chemotherapy alone (ChT without TRT).
Role of adjuvant radiotherapy for stage II thymoma after complete tumor resection.
Int J Radiat Oncol Biol Phys
December 2010
Purpose: To determine whether patients with Masaoka stage II thymoma benefit from adjuvant radiation therapy after complete tumor resection.
Methods And Materials: A total of 107 patients with stage II thymoma who underwent complete resection of their tumors between September 1964 and October 2006 were retrospectively analyzed. Sixty-six patients were treated with adjuvant radiotherapy, and 41 patients received surgery alone.
[Clinical analysis of 126 patients with primary small cell carcinoma of the esophagus].
Zhonghua Zhong Liu Za Zhi
February 2009
Objective: To investigate the prognostic factors and the principles of treatment of primary esophageal small cell carcinoma (SCEC) retrospectively.
Methods: The data of 126 patients with histologically confirmed SCEC treated in our department between May 1985 and June 2005 were retrospectively analyzed. 85 patients were in limited disease stage (LD) and 41 patients as extensive disease stage (ED) according to the Veterans Administration Lung Study Group staging system.
[Postoperative three-dimensional conformal radiotherapy for resected non-small cell lung cancer].
Zhonghua Zhong Liu Za Zhi
October 2008
Objective: To investigate the association between survival and postoperative three-dimensional conformal radiotherapy (3DCRT) in patients with resected non-small cell lung cancer (NSCLC).
Methods: Eighty-four patients were treated with surgery and postoperative 3DCRT for NSCLC. Sixty-five (77.
Objective: To summarize our experience and evaluate the prognostic factors of locally advanced non small cell lung cancer (LA-NSCLC) treated with three dimentional conformal radiotherapy (3D-CRT).
Methods: 118 patients with stage IIImA/IIIB non small cell lung cancer were treated with 3D-CRT from Nov. 2001 to Mar.
[Preliminary results of three-dimensional conformal radiotherapy for small-cell lung cancer].
Zhonghua Zhong Liu Za Zhi
September 2005
Objective: To evaluate the feasibility, therapeutic effects and complications of three-dimensional conformal radiotherapy (3DCRT) for small-cell lung cancer (SCLC).
Methods: The data of 19 SCLC patients treated between June 2001 and August 2003, with 3DCRT were reviewed and analyzed. Eighteen patients were treated by radiotherapy plus chemotherapy while only 1 patient by radiotherapy alone.
Objective: To analyze the influence of the number of lymph node metastasis on survival and prophylactic postoperative radiotherapy after radical resection of thoracic esophageal carcinoma.
Methods: Four hundred and ninety-five patients with thoracic esophageal squamous cell cancer who had undergone radical resection were randomly divided into surgery group alone (S, 275) and surgery plus radiotherapy group (S + R, 220). The patients were classified into three groups: Group A: 234 patients (47.
[Evidence-based clinical practice of radiotherapy of small-cell lung cancer].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
December 2002
Objective: To evaluate the effects of radiotherapy in the treatment of small-cell lung cancer and the optimal radiation doses, irradiation volume and fractionations.
Methods: Using evidence-based principles to search and evaluate clinical evidence on radiotherapy of small-cell lung cancer and giving grades of recommendation in clinical practice.
Results And Conclusion: The combination of chemotherapy and thoracic irradiation were the treatment strategy in limited stage small-cell lung cancer (LD SCLC).